富血小板纤维蛋白治疗Ⅱ度根分叉病变的效果评价

doi:10.19439/j.sjos.2018.05.013

上海口腔医学 ›› 2018, Vol. 27 ›› Issue (5): 508-512.doi: 10.19439/j.sjos.2018.05.013

富血小板纤维蛋白治疗Ⅱ度根分叉病变的效果评价

沈敏华, 黄远亮, 厉祯, 张迎娣, 何燕萍, 王磊

同济大学附属东方医院口腔科,上海 200120

收稿日期:2018-03-19 出版日期:2018-10-25 发布日期:2018-11-05
通讯作者: 王磊,E-mail:leiwang0222@163.com
作者简介:沈敏华（1982-）,女,硕士,E-mail:jelly_shen@sina.com
基金资助:
浦东新区卫生和计划生育委员会青年科技项目（PW2015B-7）; 浦东新区科技发展基金创新课题项目（PKJ2013-Y15）

Effect of platelet rich fibrin combining with Bio-oss to treat furcation involvement

SHEN Min-hua, HUANG Yuan-liang, LI Zhen, ZHANG Ying-di, HE Yan-ping, WANG Lei

Department Of Stomatology, Shanghai East Hospital Affiliated to Tongji University. Shanghai 200120, China

Received:2018-03-19 Online:2018-10-25 Published:2018-11-05

摘要/Abstract

摘要： 目的: 观察富血小板纤维蛋白（platelet rich fibrin, PRF）联合Bio-oss治疗Ⅱ度根分叉病变的临床效果。方法: 选取临床Ⅱ度根分叉病变的下颌第一磨牙患者30 例,经过牙周基础治疗后,随机分为实验组和对照组（各15例）。实验组采用引导牙周组织再生术,术中PRF联合Bio-oss植入骨缺损区并覆盖PRF 膜;对照组仅采用单纯牙周翻瓣术。术后6个月回访,通过临床牙周指数检查及锥形束CT（CBCT）检查评价临床疗效。采用SPSS2.0软件包进行统计学分析。结果: 2组患者术后牙周探诊深度（probing depth,PD）、临床附着丧失（clinical attachment loss,CAL）、根分叉水平探入深度（horizontal probing depth,HPD）均较术前显著改善（P<0.05）,且2组间差异具有统计学意义（P<0.05）;实验组术后根分叉区骨增量与对照组之间有显著差异（P<0.05）。结论: PRF联合Bio-oss明显促进牙周Ⅱ度根分叉病变区成骨,改善牙周状况,临床效果显著。

关键词: 富血小板纤维蛋白, Ⅱ度根分叉病变, Bio-oss骨粉, 锥形束CT

Abstract: PURPOSE: To evaluate the effect of platelet rich fibrin (PRF) combining with Bio-oss in treating Class II furcation involvement. METHODS: Thirty patients who had Class Ⅱ furcation involvement in the mandibular first molar were included. They were all free of systemic disease. After initial periodontal therapy, they were randomly divided into 2 groups. In the experimental group, PRF combining with Bio-oss were placed in the areas with furcation defect and covered with PRF. In the control group, only flap surgery was performed. All patients were followed up for 6 months after operation. The efficacy was evaluated with clinical parameters and cone-beam computed tomography (CBCT). The data were analyzed with SPSS 2.0 software package. RESULTS: Periodontal indexes including probing depth (PD), clinical attachment loss (CAL), horizontal probing depth (HPD) significantly decreased in both groups after operation (P<0.05); alveolar bone significantly increased in the experimental group (P<0.05). CONCLUSIONS: The clinical effect of PRF combined with Bio-oss on Class II furcation involvement are remarkable.

Key words: Platelet rich fibrin, Class II furcation defects, Bio-oss powder, Cone-beam computed tomography

中图分类号:

R781.4

沈敏华, 黄远亮, 厉祯, 张迎娣, 何燕萍, 王磊. 富血小板纤维蛋白治疗Ⅱ度根分叉病变的效果评价[J]. 上海口腔医学, 2018, 27(5): 508-512.

SHEN Min-hua, HUANG Yuan-liang, LI Zhen, ZHANG Ying-di, HE Yan-ping, WANG Lei. Effect of platelet rich fibrin combining with Bio-oss to treat furcation involvement[J]. Shanghai Journal of Stomatology, 2018, 27(5): 508-512.

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富血小板纤维蛋白治疗Ⅱ度根分叉病变的效果评价

Effect of platelet rich fibrin combining with Bio-oss to treat furcation involvement

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