Bio-Oss骨粉和Bio-Oss骨胶原位点保存的效果评价

doi:10.19439/j.sjos.2020.04.016

上海口腔医学 ›› 2020, Vol. 29 ›› Issue (4): 414-147.doi: 10.19439/j.sjos.2020.04.016

Bio-Oss骨粉和Bio-Oss骨胶原位点保存的效果评价

徐丹¹, 姚淳², 顾敏¹

1.苏州大学附属第三医院,常州市第一人民医院口腔科,江苏常州 213003;
2.江苏大学附属人民医院,镇江市第一人民医院口腔科,江苏镇江 212000

收稿日期:2019-02-25 修回日期:2019-05-06 出版日期:2020-08-25 发布日期:2020-09-11
通讯作者: 顾敏,E-mail：gumin106@163.com
作者简介:徐丹（1984-）,女,硕士,主治医师,E-mail：xudan1984318@163.com
基金资助:
常州市卫计委青年人才科技项目（QN201708）; 镇江市卫生局科技创新市重点研发计划（社会发展）（SH2017041）

Clinical study of Bio-Oss powder and Bio-Oss collagen for site preservation during implantology

XU Dan¹, YAO Chun², GU Min¹

1. Department of Stomatology, The Third Affiliated Hospital of Soochow University, The First People's Hospital of Changzhou City. Changzhou 213003;
2. Department of Stomatology, The People's Hospital Affiliated to Jiangsu University, The First People's Hospital of Zhenjiang City. Zhenjiang 212000, Jiangsu Province, China

Received:2019-02-25 Revised:2019-05-06 Online:2020-08-25 Published:2020-09-11

摘要/Abstract

摘要： 目的：研究Bio-Oss 骨粉+胶原膜（海奥）和骨胶原在位点保存中的临床效果。方法：选取患牙26颗,随机分为 2 组。骨粉组13例,于拔牙窝内植入Bio-Oss骨粉,表面覆盖胶原膜（海奥）;骨胶原组13例,于拔牙窝内仅植入Bio-Oss 骨胶原。3个月后复查,观察2组患牙牙槽窝愈合情况,于位点保存术后即刻和术后3个月进行锥形束 CT（CBCT）检查 ,测量牙槽骨垂直向高度与水平颊舌向厚度、CBCT灰度值的变化,临床观察新骨外形轮廓的改变,评价位点保存的临床效果。采用 SPSS 17.0 软件包对数据进行处理。结果： 2组在新骨外形轮廓方面无显著差异（P>0.05）;术后3个月,2组牙槽骨高度、厚度均减低,灰度值升高,均有统计学差异（P均<0.01）,但2组疗效无显著差异（P均>0.05）。结论：2种材料用于位点保存时效果无显著差异,但使用骨胶原的位点保存技术操作简单,创伤小,费用低。

关键词: 牙槽骨, 位点保存, 锥形束CT

Abstract: PURPOSE: To investigate the effect of Bio-Oss bone powder combined with Heal-All Oral repair membrane and Bio-Oss collagen on site preservation during implantology. METHODS: A total of 26 cases were randomly divided into 2 groups. In Bio-Oss bone powder group (13 cases), the sockets were filled with Bio-Oss bone powder, covering with Heal-All Oral repair membrane on the surface. In Bio-Oss collagen group (13 cases), the sockets were filled with Bio-Oss collagen only. The changes in alveolar bone density,height,width and new bone contour were evaluated with cone-beam CT(CBCT) after site preservation. The data were analyzed with SPSS 17.0 software package. RESULTS: There was no significant difference in new bone contour between 2 groups(P>0.05). The changes in height, width and grey level of alveolar bone between the two groups were significantly different after 3 months of follow-up(P<0.01), but the curative effect was similar(P>0.05). CONCLUSIONS: There is no significant difference in the efficacy of site preservation between the two materials. However, the site preservation technique using collagen is simple, less invasive and less costly.

Key words: Alveolar bone, Site preservation, Cone-beam CT

中图分类号:

R782.1

徐丹, 姚淳, 顾敏. Bio-Oss骨粉和Bio-Oss骨胶原位点保存的效果评价[J]. 上海口腔医学, 2020, 29(4): 414-147.

XU Dan, YAO Chun, GU Min. Clinical study of Bio-Oss powder and Bio-Oss collagen for site preservation during implantology[J]. Shanghai Journal of Stomatology, 2020, 29(4): 414-147.

参考文献

[1] Chan HL, Lin GH, Fu JH, et al.Alterations in bone quality after socket preservation with grafting materials: a systematic review[J]. Int J Oral Maxillofac Implants, 2013, 28(3): 710-720.
[2] 张淅, 谢珊珊, 史慧刚. 重度牙周炎患牙拔后位点保存的临床观察[J]. 中国口腔种植学杂志, 2016, 21(4): 182-184.
[3] Lim HC, Lee JS, Choi SH, et al.The effect of overlaying titanium mesh with collagen membrane for ridge preservation[J]. J Periodontal Implant Sci, 2015, 45(4): 128-135.
[4] 李景辉, 杨瑛, 张方明. 应用位点保存技术预防拔牙后牙槽骨吸收的临床疗效观察[J]. 临床和实验医学杂志, 2016, 15(8): 816-818.
[5] 王丹宁, 邓春富, 赵宝红, 等. 后牙区牙槽骨位点保存的临床研究[J]. 口腔医学研究, 2012, 28(12): 1275-1277.
[6] 牛杏雨, 肖燕, 高振杰, 等. 可吸收丝素修复膜在拔牙后位点保存的有效性和安全性[J]. 中国组织工程研究, 2019, 23(6): 906-911.
[7] Li J, Zhang L, Lv S, et al.Fabrication of individual scaffolds based on a patient-specific alveolar bone defect model[J]. J Biotechnol, 2011, 151(1): 87-93.
[8] Artzi Z, Tal H, Dayan D.Porous bovine bone mineral in healing of human extraction sockets: 2. Histochemical observations at 9 months[J]. J Periodontol, 2001, 72(2): 152-159.
[9] Carmagnola D, Adriaens P, Berglundh T.Healing of human extraction sockets filled with Bio-Oss[J]. Clin Oral Implants Res, 2003, 14(2): 137-143.
[10] 李春明, 杨春艳, 刘宝林, 等. 骨髓基质细胞复合多孔矿化Bio-Oss骨胶原移植修复下颌骨缺损的实验研究[J]. 实用口腔医学杂志, 2005, 21(3): 352-355.
[11] 李怀希, 陈卓凡, 曾融生, 等. Bio-Oss骨胶原在即刻种植中的临床应用研究[J]. 中国口腔种植学杂志, 2006, 11(4): 176-178.
[12] Nevins ML, Camelo M, Lynch SE, et al.Evaluation of periodontal regeneration following grafting intrabony defects with Bio-Oss collagen: a human histologic report[J]. Int J Periodontics Restorative Dent, 2003, 23(1): 9-17.
[13] Mcallister BS, Margolin MD, Cogan AG, et al.Eighteen-month radiographic and histologic evaluation of sinus grafting with anorganic bovine bone in the chimpanzee[J]. Int J Oral Maxillofac Implants, 1999, 14(3): 361-368.
[14] 王健, 胡秀莲, 林野. Bio-Oss和Bio-Oss骨胶原保持牙槽骨量的临床研究[J]. 现代口腔医学杂志, 2009, 23(1): 4-6.
[15] Jung RE, Siegenthaler DW, Hämmerle CH.Postextraction tissue management: a soft tissue punch technique[J]. Int J Periodontics Restorative Dent, 2005, 24(6): 545-553.

Bio-Oss骨粉和Bio-Oss骨胶原位点保存的效果评价

Clinical study of Bio-Oss powder and Bio-Oss collagen for site preservation during implantology

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价

[1]	霍美玲, 雷颖, 辛欣, 张颖, 王瑞梅. 2种矫治器对轻中度Ⅰ类错𬌗患者前牙牙根及牙槽骨的影响[J]. 上海口腔医学, 2024, 33(4): 407-410.
[2]	林惠, 高云飞, 卫超, 王梦蕾, 马旭辉. 槐角提取物对雌激素缺乏性骨质疏松小鼠牙槽骨骨量的影响[J]. 上海口腔医学, 2024, 33(3): 255-259.
[3]	卜晓霜, 王晓, 潘涛华, 朱丽雷, 郭锦材. MB-PDT辅助基础治疗对下前牙牙槽骨角形吸收的临床疗效评价[J]. 上海口腔医学, 2024, 33(3): 265-268.
[4]	李苏娜, 宋文尚, 刘子略, 杜月茹, 蔡世新. 义齿咬合板联合综合物理疗法对颞下颌关节盘不可复性前移位的疗效评价[J]. 上海口腔医学, 2024, 33(3): 273-278.
[5]	张民珍, 邝惠芳, 杨黎艳, 罗文. 小肠黏膜下层可吸收生物膜在牙槽骨缺损修复中的应用效果评价[J]. 上海口腔医学, 2024, 33(3): 279-284.
[6]	陈宏丽, 尹刚, 张海娟. 阿托伐他汀促进大鼠牙槽骨缺损愈合及对Wnt/β-catenin信号通路的影响[J]. 上海口腔医学, 2024, 33(2): 130-134.
[7]	苏娟娟, 陈洪婷, 王旭, 靳强, 王琳. PGE2、COX-2表达与牙槽骨成骨活性、内氧水平的关系[J]. 上海口腔医学, 2024, 33(1): 85-89.
[8]	周团锋, 杨雪, 张华, 张智勇, 陈全. 48例Locator种植覆盖全口义齿5年临床修复效果评价[J]. 上海口腔医学, 2024, 33(1): 90-96.
[9]	彭源浩, 庄昕仪, 喻婷, 吕冬梅, 温秀杰, 程钎. 青少年颧牙槽嵴区皮质骨厚度的锥形束CT测量及其与颈椎骨龄的相关性研究[J]. 上海口腔医学, 2023, 32(6): 623-629.
[10]	夏婷婷, 汪涌. 重度牙周炎后牙位点保存术中联合应用浓缩生长因子的疗效评价[J]. 上海口腔医学, 2023, 32(6): 650-655.
[11]	黄仲敏, 张赟, 李小兵. 替牙列早期上颌慢速扩弓对上颌中段牙及牙槽嵴的影响[J]. 上海口腔医学, 2023, 32(5): 501-507.
[12]	李贵宏, 谢思静, 林梓桐, 张婷, 汤旭娜, 胡勤刚. 下颌第二磨牙C形根管治疗前后根管壁厚度测量分析[J]. 上海口腔医学, 2023, 32(4): 395-400.
[13]	俞晓霏, 汪信洋, 李斌, 陈耀忠. 壳寡糖对骨质疏松伴牙周炎大鼠骨代谢及IKK/NF-κB通路的影响[J]. 上海口腔医学, 2023, 32(2): 137-142.
[14]	王文丽, 傅亚婷, 刘华, 马潇. 上颌前牙美学区牙龈三维形态的锥形束CT测量分析[J]. 上海口腔医学, 2023, 32(2): 177-182.
[15]	张薇, 陈威, 陈志方. 可调式活动牵引器治疗上颌唇侧倒置阻生中切牙效果评价[J]. 上海口腔医学, 2023, 32(2): 193-197.