SPR牙周基础治疗对慢性牙周炎患者龈沟液C反应蛋白的影响

doi:10.19439/j.sjos.2018.05.018

摘要/Abstract

摘要： 目的: 探讨SPR牙周基础治疗对慢性牙周炎患者牙周炎症控制、炎症指标龈沟液C反应蛋白的影响。方法: 将80例慢性牙周炎患者平均分为2组,实验组采用SPR牙周基础治疗,对照组仅接受龈上洁治术,比较2组治疗后3个月、6个月牙周指数[包括平均探诊深度（PO）、临床附着水平（CAL）和龈沟出血指数（SBI）]和龈沟液C反应蛋白（CRP）的变化。采用 SPSS 20.0软件包对数据进行统计学处理。结果: 2组患者治疗后3个月、6个月牙周指标SBI、PD 和 CAL以及龈沟液CRP均降低。实验组治疗后3个月、6个月实验组牙周指标及龈沟液CRP显著低于对照组（P<0.01）;对照组治疗后3个月牙周指标及龈沟液CRP与治疗前有显著差异,但治疗后6个月牙周指标、龈沟液CRP逐渐上升。结论: 相对于龈上洁治,完整的SPR牙周基础治疗更能降低慢性牙周炎患者龈沟液C反应蛋白的水平。

关键词: 慢性牙周炎, 牙周基础治疗, 龈沟液, C反应蛋白

Abstract: PURPOSE: To investigate the effect of SPR periodontal basic treatment on periodontal inflammation control and inflammation index C-reactive protein in gingival crevicular fluid in patients with chronic periodontitis. METHODS: Eighty patients with chronic periodontitis in the pre-clinical trial population were included in this study for subgroup analysis. Repeated measures analysis of variance was used to compare the changes of periodontal index (including average probing depth, clinical adhesion level, and sulcus bleeding index) and gingival crevicular fluid C-reactive protein (CRP) between the SPR treatment group and the control group before treatment and 1 month and 3 months after treatment. Then difference between the two groups was analyzed with SPSS software package. RESULTS: After treatment with different basic treatments, the periodontal indexes SBI, PD, and CAL were significantly decreased compared with those before treatment, and there was significant difference in gingival crevicular fluid CRP, but there was no significant difference between the two groups. The periodontal index of SBI, PD, and CAL in the control group was gradually increased after 3 months and was not significantly different from that before treatment. The improvement of clinical indicators in the experimental group was more obvious and there was significant difference. CRP in the gingival crevicular fluid of the experimental group and the control group were decreased after a period of periodontal treatment, and there was significant difference before and after treatment. There was also a significant difference in CRP between the experimental group and the control group 3 months after treatment (P<0.01). However, CRP in the gingival crevicular fluid gradually increased in the control group after 3 months, and there was no significant difference between the two groups. CONCLUSIONS: Complete SPR periodontal therapy can control chronic periodontitis effectively, reduce CPR of gingival crevicular fluid, and reduce the systemic inflammatory status of patients. This may have a positive impact on the control of risk factors in patients with coronary heart disease.

Key words: Chronic periodontitis, Periodontal initial treatment, Gingival crevicular fluid, C-reactive protein

中图分类号:

R781.4

钟兆琪, 付华. SPR牙周基础治疗对慢性牙周炎患者龈沟液C反应蛋白的影响[J]. 上海口腔医学, 2018, 27(5): 530-534.

ZHONG Zhao-qi, FU Hua. Effects of SPR periodontal basic therapy on cervical crevicular fluid C-reactive protein in patients with chronic periodontitis[J]. Shanghai Journal of Stomatology, 2018, 27(5): 530-534.

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