上海口腔医学

上海口腔医学 ›› 2014, Vol. 23 ›› Issue (2): 188-191.

• 临床研究 • 上一篇    下一篇

长三角地区口腔黏膜癌前病变组织库和数据库的建立及应用

黄吉燕1, 2*, 赵厚明1*, 周海文1   

  1. 1.上海交通大学医学院附属第九人民医院·口腔医学院 口腔黏膜病科, 上海市口腔医学重点实验室, 上海 200011;
    2.上海中医药大学附属曙光医院 口腔科, 上海 201203
  • 收稿日期:2013-11-11 出版日期:2014-04-20 发布日期:2014-05-21
  • 通讯作者: 周海文, Tel:021-23271699-5696, E-mail:haiwen39@hotmail.com
  • 作者简介:黄吉燕(1976-), 女, 硕士, 主治医师, E-mail:coucouh@163.com;赵厚明(1986-), 男, 在读硕士研究生, 住院医师, E-mail:hmhedy@163.com。*并列第一作者
  • 基金资助:
    上海市科学技术委员会资助项目(08ZR1416700)

Construction and application of the tissue bank and database of oral mucosa precancerous lesions in the Yangtze delta

HUANG Ji-yan1, 2, ZHAO Hou-ming1, ZHOU Hai-wen1   

  1. 1.Department of Oral Medicine, Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine;Shanghai Key Laboratory of Stomatology. Shanghai 200011;
    2.Department of Stomatology, Shuguang Hospital, Shanghai Chinese Medicine University. Shanghai 201203, China
  • Received:2013-11-11 Online:2014-04-20 Published:2014-05-21

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摘要： 目的: 建立长三角地区口腔黏膜癌前病变的临床病例组织库及数据库, 并评估其应用价值。方法: 采集口腔黏膜癌前病变患者临床病例资料及病变组织、唾液及血液标本建立组织库, 以Microsoft Access平台, Brower/Server架构, ASP语言建立数据库管理病历资料和组织库。结果: 建立起长三角地区口腔黏膜癌前病变组织库, 规范了标本采集及保存方法。建立的口腔黏膜癌前病变数据库具有界面友好, 运行稳定, 录入查询快速准确, 可实行网络资源共享等特点。结论: 首次建立起的口腔黏膜癌前病变和数据库, 不仅标准化保存我国口腔黏膜癌前病变生物学资源, 而且数据库的建立为临床、科研和教学提供了便利, 具有良好的开发运用前景。

关键词: 口腔黏膜, 癌前病变, 数据库, 组织库

Abstract: PURPOSE: To construct a database and a tissue bank of oral mucosa precancerous lesions and to estimate the application values. METHODS: Patients in the Yangtze delta suffering oral mucosa precancerous lesions were enrolled into this study. The patients’ clinical data and samples of oral precancerous mucosa, salivary and blood were collected to create a tissue bank, based on which a database was constructed using Microsoft Access software, Brower/Server structure and ASP language. RESULTS: The tissue bank and database of oral mucosa precancerous lesions were successfully built. The procedure to harvest, store and transport the samples had been standardized. The database showed good interactive interface, convenient for data collection, query and share in the internet. CONCLUSIONS: We constructed the tissue bank and database of oral mucosa precancerous lesions for the first time, which not only help preserve the biological resource of oral mucosa precancerous lesions, but also provide enormous convenience in clinical work, researching and teaching.

Key words: Oral mucosa, Precancerous lesion, Database, Tissue bank

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