脉冲染料激光抑制颌面部外伤早期瘢痕的效果评价

doi:10.19439/j.sjos.2018.02.017

上海口腔医学 ›› 2018, Vol. 27 ›› Issue (2): 200-203.doi: 10.19439/j.sjos.2018.02.017

脉冲染料激光抑制颌面部外伤早期瘢痕的效果评价

董依云^1,*, 陶岚^1,*, 周国瑜², 王海宁¹, 朱亚琴¹

1.上海交通大学医学院附属第九人民医院·口腔医学院口腔综合科,2.口腔颌面-头颈肿瘤科,国家口腔医学疾病临床研究中心,上海市口腔医学重点实验室,上海市口腔医学研究所,上海 200011

收稿日期:2017-09-18 修回日期:2017-11-30 出版日期:2018-04-25 发布日期:2018-05-14
通讯作者: 朱亚琴,E-mail：zyq1590@163.com
作者简介:董依云（1988-）,女,硕士,住院医师,E-mail：yiyun_dong@yeah.net;陶岚（1971-）,女,硕士,副主任医师,E-mail：13917166195@139.com。*并列第一作者

Effect of pulsed dye laser on inhibiting early scar after maxillofacial trauma

DONG Yi-yun¹, TAO Lan¹, ZHOU Guo-yu², WANG Hai-ning¹, ZHU Ya-qin¹

1.Department of General Dentistry, 2.Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center of Stomatology; Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology. Shanghai 200011, China

Received:2017-09-18 Revised:2017-11-30 Online:2018-04-25 Published:2018-05-14

摘要/Abstract

摘要： 目的:评价脉冲染料激光抑制颌面部外伤早期瘢痕的效果。方法:随机选取50例颌面部外伤术后患者,采用自身对照试验,将病灶平均分为治疗组和对照组。治疗组在拆线后即刻,拆线后15、30和60 d分别给予脉冲染料激光治疗,对照组不做治疗。采用皮肤数码显微镜拍摄治疗前和疗程结束后3个月治疗组和对照组瘢痕病灶照片并测量其面积,采用SPSS 13.0软件包对实验组和对照组病灶治疗前后面积差值进行统计学分析,由患者对病灶改善情况进行评分。结果:实验组37例患者达到治愈和显著改善,有效率位74%;对照组11例患者显著改善,有效率位22%。实验组和对照组治疗前、后瘢痕面积差值具有显著差异（P<0.05）,患者平均满意度较高。未见明显不良反应。结论:脉冲染料激光在抑制颌面部外伤早期瘢痕中疗效确切,为减少颌面部外伤早期瘢痕提供了安全可靠的方法。

关键词: 脉冲染料激光, 颌面部外伤, 早期瘢痕

Abstract: PURPOSE: The study was designed to explore an effective method to control early scar after maxillofacial trauma and improve the satisfaction of clinical treatment. METHODS: Fifty skin lesions after maxillofacial trauma were divided into the experimental group and control group. Patients in the experimental group were treated with pulsed dye laser when taking out stitches, 15, 30 and 60 days later. Digital microscope photos were taken and lesion area was measured before and 3 months after laser irradiation. Adverse effects were recorded during and after each treatment as well. All patients were asked to rate their satisfaction at 3-month of follow-up. Statistical analysis was performed using SPSS 13.0 software package. RESULTS: The efficiency of the experimental group was 74% and 37 lesions were cured or significantly improved, while the efficiency rate was 22% in the control group. Area reduction of maxillofacial lesions before and after treatment between the two groups was significantly different (P<; 0.05). Patients in the experimental group were highly satisfied with the final outcomes. No severe adverse events were observed. CONCLUSIONS: Pulsed dye laser is safe and effective in inhibiting early scar following maxillofacial trauma .

Key words: Pulsed dye laser, Maxillofacial trauma, Early scar

中图分类号:

R782.4

董依云, 陶岚, 周国瑜, 王海宁, 朱亚琴. 脉冲染料激光抑制颌面部外伤早期瘢痕的效果评价[J]. 上海口腔医学, 2018, 27(2): 200-203.

DONG Yi-yun, TAO Lan, ZHOU Guo-yu, WANG Hai-ning, ZHU Ya-qin. Effect of pulsed dye laser on inhibiting early scar after maxillofacial trauma[J]. Shanghai Journal of Stomatology, 2018, 27(2): 200-203.

参考文献

[1] Bousquet-Rouaud R.Scars and lasers[J].Soins, 2013,(772): 44-45.
[2] Ud-Din S, Bayat A.New insights on keloids, hypertrophic scars, and striae[J]. Dermatol Clin, 2014, 32(2): 193-209.
[3] Mansouri P, Ranjbar M, Abolhasani E.Pulsed dye laser in treatment of steroid-induced atrophy[J]. J Cosmet Dermatol, 2015, 14(4): E15-20.
[4] Brewin MP, Lister TS.Prevention or treatment of hypertrophic burn scarring: a review of when and how to treat with the pulsed dye laser[J]. Burns, 2014, 40(5): 797-804.
[5] Vazquez-Martinez O, Eichelmann K, Garcia-Melendez M.Pulsed dye laser for early treatment of scars after dermatological surgery[J]. J Drugs Dermatol, 2015, 14(11): 1209-1212.
[6] Kim DH, Ryu HJ, Choi JE, et al.A comparison of the scar prevention effect between carbon dioxide fractional laser and pulsed dye laser in surgical scars[J]. Dermatol Surg, 2014, 40(9): 973-978.
[7] Ryu HW, Cho JH, Lee KS.Prevention of thyroidectomy scars in Korean patients using a new combination of intralesional injection of low-dose steroid and pulsed dye laser starting within 4 weeks of suture removal[J]. Dermatol Surg, 2014, 40(5): 562-568.
[8] Martin MS, Collawn SS.Combination treatment of CO2 fractional laser, pulsed dye laser, and triamcinolone acetonide injection for refractory keloid scars on the upper back[J]. J Cosmet Laser Ther, 2013,15(3): 166-170.
[9] Al-Mohamady Ael-S, Ibrahim SM, Muhammad MM. Pulsed dye laser versus long-pulsed Nd: YAG laser in the treatment of hypertrophic scars and keloid: A comparative randomized split-scar trial[J]. J Cosmet Laser Ther, 2016, 18(4): 208-212.
[10] Lee SJ, Jeong SY, No YA, et al.Combined treatment with botulinum toxin and 595-nm pulsed dye laser for traumatic scarring[J]. Ann Dermatol, 2015, 27(6): 756-758.
[11] Cohen BE, Brauer JA, Geronemus RG.Acne scarring: A review of available therapeutic lasers[J]. Lasers Surg Med, 2016, 48(2): 95-115.
[12] Vranova J, Remlova E, Jelinkova H, et al.Comparison of quality of facial scars after single low-level laser therapy and combined low-level with high-level (PDL 595 nm) laser therapy[J]. Dermatol Ther, 2015, 28(4): 201-209.
[13] Cannarozzo G, Sannino M, Tamburi F, et al.Flash-lamp pulsed-dye laser treatment of keloids: results of an observational study[J]. Photomed Laser Surg, 2015, 33(5): 274-277.

[1]	刘玥旻, 柴盈, 魏文斌, 刘芷扬, 韩孜祥, 陈敏洁. 大鼠三叉神经病理性疼痛致病关键转录分子分析[J]. 上海口腔医学, 2023, 32(1): 33-39.
[2]	应凯, 王亮, 朱永武, 李倩倩, 毛斌. 虚拟手术结合导板辅助7例髁突颈部骨折复位固定的效果评价[J]. 上海口腔医学, 2023, 32(1): 105-108.
[3]	黄锦程, 赵华强, 李国菊. Stafne骨腔影像学特征：基于CBCT的回顾性分析[J]. 上海口腔医学, 2022, 31(4): 439-444.
[4]	姚志涛, 安玮, 买买提吐逊·吐尔地. 保守治疗对儿童单侧髁突骨折患者颌骨对称性的影响[J]. 上海口腔医学, 2021, 30(1): 77-80.
[5]	陈伟, 房睿. 微型钛板在内固定治疗下颌骨粉碎性骨折中的应用：21例临床分析[J]. 上海口腔医学, 2020, 29(3): 333-336.
[6]	印志法, 王思明. rhEGF对口腔颌面部外伤患者血清EGF及炎症因子水平的影响[J]. 上海口腔医学, 2017, 26(6): 654-657.
[7]	何思铃, 肖水生. 下颌骨骨折术后感染相关因素分析[J]. 上海口腔医学, 2017, 26(4): 429-433.
[8]	王留宏, 杨政, 杨惠, 娄新田, 王一霖, 戚向群. 口腔颌面清创术后软组织感染的相关因素分析[J]. 上海口腔医学, 2017, 26(4): 461-464.
[9]	李丽, 袁卫军, 陈巧露, 姚瑶, 黄莹玭. 口腔颌面部创伤患者创伤后积极心理反应及相关影响因素分析[J]. 上海口腔医学, 2017, 26(1): 102-105.
[10]	卢阳, 卢晓峰, 范先群. 621例颅颌面骨折临床分析[J]. 上海口腔医学, 2017, 26(1): 106-110.
[11]	张伯俊, 王卫红, 许彪. 口内入路与口外入路治疗下颌角骨折的疗效比较[J]. 上海口腔医学, 2016, 25(4): 500-510.
[12]	景捷,曲爱丽,丁晓梅,黑玉娜. 髁突矢状骨折坚固内固定后骨折愈合进程的生物力学分析[J]. 上海口腔医学, 2015, 24(2): 164-169.
[13]	张德辉,刘希云. 重建板坚固内固定治疗感染性下颌骨骨折[J]. 上海口腔医学, 2015, 24(1): 115-117.
[14]	吴烨, 林李嵩, 牛刚, 谢福平. 亚砷酸致颌骨坏死的诊治:附10例报道[J]. 上海口腔医学, 2014, 23(6): 755-758.
[15]	谭新颖, 胡敏, 刘昌奎, 刘华蔚, 刘三霞, 陶冶. 数字化虚拟手术设计辅助正颌外科手术12例临床分析[J]. 上海口腔医学, 2014, 23(3): 322-327.

脉冲染料激光抑制颌面部外伤早期瘢痕的效果评价

Effect of pulsed dye laser on inhibiting early scar after maxillofacial trauma

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价