牙周基础治疗对2型糖尿病伴慢性牙周炎患者血糖控制的影响

doi:10.19439/j.sjos.2025.02.016

摘要/Abstract

摘要： 目的：探讨牙周基础治疗对2型糖尿病伴慢性牙周炎患者血糖控制的影响及敏感人群。方法：选择2022年3月—2023年3月在丽水市人民医院内分泌科就诊的2型糖尿病伴慢性牙周炎患者120例,随机分为试验组和对照组,每组各60例。所有患者均接受口腔卫生宣教,采集患者一般项目、社区牙周指数（community periodontal index,CPI）、附着丧失（attachment loss,AL)、空腹血糖（fasting plasma glucose,FPG）和糖化血红蛋白（HbA1c）。试验组行牙周基础治疗。3个月后,检查CPI、AL、FPG和HbA1c。采用Stata 15.0软件对数据进行统计学分析。结果：牙周基础治疗后,试验组CPI、FPG和HbA1c显著低于治疗前（P<0.01）和对照组（P<0.05）,试验组AL显著低于治疗前（P<0.05）和对照组（P<0.05）。治疗后FPG变化与糖尿病病程（P<0.01）和治疗前CPI（P<0.05）呈正相关,与是否患高血压呈负相关（P<0.05）,其变化还与治疗前FPG呈负相关（P<0.01）。治疗后HbA1c变化与糖尿病病程呈正相关（P<0.05）,与治疗前HbA1c呈负相关（P<0.01）。结论：牙周基础治疗有助于2型糖尿病伴牙周炎患者的血糖控制。CPI基线水平更高、病程更长的患者,治疗后糖代谢水平改善更多。

关键词: 牙周基础治疗, 2型糖尿病, 慢性牙周炎, 血糖

Abstract: PURPOSE: To investigate the effect of nonsurgical periodontal therapy on blood glucose control in patients with type 2 diabetes mellitus (T2DM) and chronic periodontitis, as well as the sensitive population. METHODS: A total of 120 patients with T2DM and chronic periodontitis who were admitted to the Department of Endocrinology at Lishui City People's Hospital from March 2022 to March 2023 were randomly divided into experimental group and control group, with 60 patients in each group. All patients received oral health education, and their general information, community periodontal index (CPI), attachment loss (AL), fasting plasma glucose (FPG), and haemoglobin A1c (HbA1c) were collected. The experimental group received periodontal scaling and root planing. Three months later, CPI, AL, FPG, and HbA1c were measured. Stata 15.0 software was used for statistical analysis. RESULTS: After periodontal scaling and root planing, the CPI, FPG, and HbA1c in the experimental group were significantly lower than those before treatment(P<0.01) and those in the control group(P<0.05). AL in the experimental group was also significantly lower than before treatment(P<0.05) and the control group (P<0.05). The change of FPG after treatment was positively correlated with the duration of diabetes (P<0.01) and the baseline CPI(P<0.05), but negatively correlated with whether suffering from hypertension(P<0.05). It was also negatively correlated with the FPG level before treatment (P<0.01). The change of HbA1c after treatment was positively correlated with the duration of diabetes(P<0.05) and negatively correlated with the HbA1c level before treatment(P<0.01). CONCLUSIONS: Nonsurgical periodontal therapy is helpful to blood sugar control of type 2 diabetes patients with periodontitis. Patients with higher baseline CPI levels and longer disease durations show greater improvement in glycemic control after treatment.

Key words: Nonsurgical periodontal therapy, Type 2 diabetes, Chronic periodontitis, Glycemic control

中图分类号:

R781.4.2

商裕, 江银华, 陈元明, 付海标, 李凤丹. 牙周基础治疗对2型糖尿病伴慢性牙周炎患者血糖控制的影响[J]. 上海口腔医学, 2025, 34(2): 202-207.

Shang Yu, Jiang Yinhua, Chen Yuanming, Fu Haibiao, Li Fengdan. Effect of nonsurgical periodontal therapy on glycemic control in type 2 diabetes patients with chronic periodontitis[J]. Shanghai Journal of Stomatology, 2025, 34(2): 202-207.

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