灼口综合征病因与影响因素分析

doi:10.19439/j.sjos.2025.02.005

摘要/Abstract

摘要： 目的：分析灼口综合征（burning mouth syndrome,BMS）患者病因及相关影响因素。方法：选择2022年11月—2023年10月于中国医科大学附属盛京医院口腔科就诊的BMS患者109例,另选取同期自愿参与调查的健康人84名作为对照组。记录研究对象的基本资料,评估口腔卫生状况、牙周健康状况及精神心理状况,采用SPSS 27.0软件包,通过t检验、卡方检验及二元logistic回归,分析影响BMS发病相关因素。结果：单因素分析所示,残冠残根、牙周炎、焦虑状态、抑郁状态、睡眠障碍、绝经、糖尿病、消化系统疾病和腔隙性脑梗塞与BMS发病有关(P<0.05)。选择单因素分析中P<0.1的变量进行多因素logistic回归分析,结果显示,牙周炎、新型冠状病毒肺炎（COVID-19）、焦虑状态、抑郁状态、睡眠障碍、消化系统疾病、腔隙性脑梗塞为影响BMS发病的因素(P<0.05,OR>1)。结论：BMS的病因涉及局部及全身因素、神经病理因素与精神心理因素之间的相互影响,因此BMS的诊疗需要心理科、神经内科、消化内科等多学科的配合,积极治疗系统性疾病或相关疾病。临床工作者除加强患者口腔卫生及牙周健康管理外,还应关注新冠疫情大流行导致的BMS患者疼痛强度、睡眠质量和焦虑状态恶化,及时进行心理疏导,从而更好地控制疾病发展。

关键词: 灼口综合征, 牙周炎, 新型冠状病毒肺炎, 焦虑, 抑郁

Abstract: PURPOSE: To analyze the etiology and related influencing factors of burning mouth syndrome (BMS). METHODS: A total of 109 patients with BMS who visited the Department of Stomatology of Shengjing Hospital of China Medical University from November 2022 to October 2023 were selected, and 84 healthy volunteers who participated in the survey during the same period were selected as the control group. The basic information of the research subjects was recorded, and oral health status, periodontal health status and psychological status of the research subjects were evaluated. Student's t test, Chi-square test and binary logistic regression analysis were used to analyze the factors affecting the incidence of BMS with SPSS 27.0 software package. RESULTS: Mono-factor analysis showed that residual crown, residual root, periodontitis, anxiety status, depressive status, sleep disorders, menopause, diabetes, digestive system diseases and lacunar infarction were related to the incidence of BMS (P<0.05). The variables with P<0.1 in mono-factor analysis were selected for multivariate logistic regression analysis. The results showed that periodontitis, COVID-19, anxiety status, depressive status, sleep disorders, lacunar infarction, and digestive system diseases were factors affecting the incidence of BMS (P<0.05 and OR>1). CONCLUSIONS: The diagnosis and treatment of BMS require multidisciplinary cooperation of specialists such as psychiatry, neurology and gastroenterology, and active treatment of systemic or related diseases. In addition to strengthening oral hygiene and periodontal health management for patients, clinical practitioners should also pay attention to the aggravation of BMS patients' pain intensity, sleep quality and anxiety caused by COVID-19 pandemic, and provide timely psychological counseling to better control the development of BMS.

Key words: Burning mouth syndrome, Periodontitis, COVID-19, Anxiety, Depression

中图分类号:

R781.5

周慧蓉, 林晓萍. 灼口综合征病因与影响因素分析[J]. 上海口腔医学, 2025, 34(2): 139-145.

Zhou Huirong, Lin Xiaoping. A study on the relationship between etiology and influencing factors of burning mouth syndrome[J]. Shanghai Journal of Stomatology, 2025, 34(2): 139-145.

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