关键词: 牙黑色素沉着, Logistic回归分析, 危险因素, 病例对照研究

Abstract: PURPOSE: To investigate the prevalence of dental black stain in children and analyze the risk factors of dental black stain. METHODS: We conducted this investigation through a case-control study. A total of 164 children (82 children with dental black stain and 82 children without dental black stain) were recruited from Shanghai Stomatological Hospital. Data regarding their oral hygiene habits, dietary habits, diseases and medication situations were collected by a questionnaire survey. Samples of saliva were collected for pH analysis. Statistical analysis were performed using SPSS 21.0 software package. RESULTS: Univariate analysis showed that the proportion of children in the black stain group who used bottled water as the main source of drinking water was lower than that in the control group (18.3% vs 35.4%), and the proportion of children who used Chinese herbs or eating more vegetables(≥2 times/day) was higher than that in the control group(23.2% vs 9.8%,29.3% vs 14.6%), the differences were statistically significant (P<0.05). Multivariate logistic regression analysis showed that taking Chinese herbal medicine and eating more vegetables(≥2 times/day) were risk factors for tooth black stains(P<0.05), and use of bottled water as the main source of drinking water was a protective factor. CONCLUSIONS: Taking Chinese herbal medicine and eating more vegetables(≥2 times/day) are risk factors for tooth pigmentation, while drinking more bottled water can reduce the risk of pigmentation.

Key words: Black tooth stains, Logistic regression analysis, Risk factors, Case-control study