唾液隐血对牙龈炎症状态测试的可靠性分析

上海口腔医学 ›› 2014, Vol. 23 ›› Issue (1): 87-90.

唾液隐血对牙龈炎症状态测试的可靠性分析

黄佳妮, 尹元正, 丁进

上海交通大学医学院附属第九人民医院·口腔医学院牙周病科, 上海市口腔医学重点实验室, 上海 200011

收稿日期:2013-06-03 修回日期:2013-08-01 出版日期:2014-02-20 发布日期:2014-10-21
通讯作者: 尹元正,Tel：23271699-5282,E-mail: yinyuanzheng@gmail.com
作者简介:黄佳妮(1987-),女,硕士,住院医师,E-mail: jtujiani@gmail.com

The reliability of the salivary occult blood to test gingival inflammation

HUANG Jia-ni, YIN Yuan-zheng, Ding Jin

Department of Periodontology, Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology. Shanghai 200011, China

Received:2013-06-03 Revised:2013-08-01 Online:2014-02-20 Published:2014-10-21

摘要/Abstract

摘要： 目的：通过对唾液隐血与牙龈出血的相关性分析,探讨以唾液隐血测试(salivary occult blood test,SOBT)判断牙龈炎症状态的可行性。方法：对45例受试者的刺激和非刺激性唾液进行隐血测试,结合牙龈探诊出血(bleeding on probing,BOP)阳性位点百分比,以BOP%≥15%者作为慢性龈炎组,其余为牙龈健康对照组作关联分析,并对比患者牙周基础治疗前后的BOP%及SOBT变化,探讨SOBT与牙龈炎症的相关性,评估以SOBT检测牙龈炎症的灵敏度与特异度,应用SAS6.12软件包对数据进行统计学分析。结果：慢性龈炎组与牙龈健康对照组的刺激性SOBT有显著差异(P<0.01),非刺激SOBT有显著差异(P<0.05)。30例接受牙周基础治疗的慢性牙龈炎患者,BOP%显著下降(P<0.01),63%刺激性与90%非刺激性SOBT阳性者牙龈炎症得到改善,均有显著差异(P<0.01)。非刺激SOBT的灵敏度为32.35%,特异度为100%;刺激性SOBT的灵敏度为88.24%,特异度为81.82%。结论：SOBT与牙龈炎症存在一定关联性,可作为判断个体牙龈炎症及牙周疗效的客观依据,对在大规模人群中早期牙龈炎症的判定和筛检具有一定价值。

关键词: 隐血试验, 牙龈炎症, 唾液, 流行病学

Abstract: PURPOSE: To evaluate the reliability of salivary occult blood test(SOBT) for gingival inflammation. METHODS: Forty-five pre- and post-stimulation saliva samples were tested for occult blood, with bleeding on probing (BOP) as an indicator of gingival inflammation. Subjects with BOP%<15% were defined as control group. The examinations were repeated 3 months after periodontal initial therapy. The relationship between the results of SOBT and gingival inflammation was analyzed. SAS6.12 software package was used for statistical analysis. RESULTS: The SOBT of pre-stimulation was higher in gingivitis group than in control group (P<0.05). BOP% and SOBT of post-therapy was significantly decreased (P<0.01), with 90% of pre- and 63% of post-stimulation SOBT turning negative. The sensitivity and specificity of pre- stimulation SOBT in screening gingivitis were 32.35% and 100%. The sensitivity and specificity of the post-stimulation SOBT were 88.24% and 81.82%. CONCLUSIONS: SOBT is correlated with gingival inflammation, which may be used as an objective parameter to evaluate gingival inflammation and the efficacy of periodontal therapy at individual level. It may offer a simple screening method for gingival inflammation applied in periodontal epidemiologic studies in large population.

Key words: Occult blood test, Gingival inflammation, Salivary, Epidemiology

中图分类号:

R781.4

黄佳妮, 尹元正, 丁进. 唾液隐血对牙龈炎症状态测试的可靠性分析[J]. 上海口腔医学, 2014, 23(1): 87-90.

HUANG Jia-ni, YIN Yuan-zheng, Ding Jin. The reliability of the salivary occult blood to test gingival inflammation[J]. Shanghai Journal of Stomatology, 2014, 23(1): 87-90.

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