面部不对称畸形患者下颌骨核素骨扫描临床分析

上海口腔医学 ›› 2013, Vol. 22 ›› Issue (3): 326-329.

面部不对称畸形患者下颌骨核素骨扫描临床分析

屈伟¹，刘浏²，丁石梅¹，王社教¹

(1.西安交通大学医学院第二附属医院核医学科，陕西西安 710004；2.上海交通大学医学院附属第九人民医院?口腔医学院口腔颌面-头颈肿瘤科，上海 200011)

收稿日期:2012-12-28 修回日期:2013-02-22 出版日期:2013-06-10 发布日期:2013-06-10
通讯作者: 屈伟，E-mail: quwei96311@163.com
作者简介:屈伟(1978-),男,硕士, 主治医师

Clinical analysis of radionuclide bone scan in patients with facial asymmetry

QU Wei¹, LIU liu², DING Shi-mei¹, WANG She-jiao¹

1.Department of Nuclear Medicine, The Second Affiliated Hospital of Medical School of Xi’an Jiao Tong University. Xi’an 710004, Shanxi Province; 2. Department of Oromaxillofacial Head and Neck Oncology, Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine. Shanghai 200011,China

Received:2012-12-28 Revised:2013-02-22 Online:2013-06-10 Published:2013-06-10

摘要/Abstract

摘要： 目的：研究面部不对称畸形患者下颌骨的放射性核素分布，帮助临床医师确定治疗时机和治疗方式。方法：29例面部对称者作为正常对照组。实验组为207例面部不对称畸形患者，测量29例面部对称和207例面部不对称畸形患者下颌骨不同部位的放射性计数，比较髁突、下颌支、下颌体99mTc-MDP摄入量百分比。采用SPSS13.0软件包对数据进行统计学处理。结果：成年和未成年患者的面部不对称畸形患者下颌骨99mTc-MDP摄入量有显著差异，男性和女性的下颌骨99mTc-MDP摄入量无显著差异。在下颌骨发育活性异常的患者中，99mTc-MDP摄取量差异值在髁突、下颌体、下颌支依次为(22.50±1.67)%、(6.93±1.02)%和(13.67±0.95)%。髁突的摄入量差异值最大。结论：下颌骨的生长发育与身体生长发育有所不同。放射性核素骨扫描可对下颌骨发育情况做出评价，为临床医师确定治疗时机与方式提供依据。

关键词: 放射性核素骨扫描, 髁突, 面部不对称畸形

Abstract: PURPOSE: To study the radionuclide distribution in mandible of patients with facial asymmetry and help to select proper time and type of treatment. METHODS： The control group included 29 people with no facial asymmetry, while the experimental group consist of 207 patients with facial asymmetry. The radioactive count in 29 normal controls and 207 patients with facial asymmetry were measured and compared using 99mTc-MDP intake percentage in mandibular condyle, ramus and body. SPSS13.0 software package was used for statistical analysis. RESULTS: There was significant difference between adult and adolescent patients in 99mTc-MDP intake of the condyles. There was no significant difference between male and female in the 99mTc-MDP intake of the condyles. The 99mTc-MDP intake difference percentage was (22.50±1.67)%, (6.93±1.02)% and (13.67±0.95)% in mandibular condyle, ramus and body, respectively. The intake difference value of the condyle was the biggest. CONCLUSIONS: The mandible growth trend is different from the body’s growth and development trend. We can analyze the trend of mandible development by radionuclide bone scan and select proper time and type of treatment.

Key words: Radionuclide bone scan, Mandibular condyle, Facial asymmetry

中图分类号:

R782.2

屈伟, 刘浏, 丁石梅, 王社教. 面部不对称畸形患者下颌骨核素骨扫描临床分析[J]. 上海口腔医学, 2013, 22(3): 326-329.

QU Wei, LIU liu, DING Shi-mei, WANG She-jiao. Clinical analysis of radionuclide bone scan in patients with facial asymmetry[J]. Shanghai Journal of Stomatology, 2013, 22(3): 326-329.

参考文献

[1] Maeda M, Katsumata A, Ariji Y, et al. 3D-CT evaluation of facial asymmetry in patients with maxillofacial deformities[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endol, 2006, 102(3): 382-390.
[2] 彭燕. 下颌骨生长发育的预测方法[J]. 口腔颌面外科杂志, 2006, 16(1): 80-82.
[3] 张震康, 张熙恩, 傅民魁. 正颌外科学[M]. 北京: 人民卫生出版社, 1994: 304-306.
[4] Wolford LM, Mehra P, Reiche-Fischel O, et al. Efficacy of high condylectomy for management of condylar hyperplasia[J]. Am J Orthod Dentofacial Orthop, 2002, 121(2): 136-151.
[5] Sato K, Mito T, Mitani H. An accurate method of predicting mandibular growth potential based on bone maturity[J]. Am J Orthod Dentofacial Orthop, 2001, 120(3): 286-293.
[6] Pripatnanont P, Vittayakittipong P, Markmanee U, et al. The use of SPECT to evaluate growth cessation of the mandible in unilateral condylar hyperplasia[J]. Int J Oral Maxillofac Surg, 2005, 34(4): 364-368.
[7] Hodder SC, Rees JI, Oliver TB, et al. SPECT bone scintigraphy in the diagnosis and management of mandibular condylar hyperplasia[J]. Br J Oral Maxillofac Surg, 2000, 38(2): 87-93.
[8] You KH, Lee KJ, Lee SH, et al. Three-dimensional computed tomography analysis of mandibular morphology in patients with facial asymmetry and mandibular prognathism[J]. Am J Orthod Dentofacial Orthop, 2010, 138(5): 540-541.
[9] Fukushima K, Yasui K, Oatuka K, et al. Morphological characteristics of patients with jaw deformities-frontal cephalometric evaluation of facial symmetry[J]. Meikai Daigaku Shigaku Zasshi, 2003, 32(1): 118-123.
[10] Lippold C, Kruse-Losler B, Danesh G, et al. Treatment of hemimandibular hyperplasia: the biological basis of condylectomy[J]. Br J Oral Maxillofac Surg, 2007, 45(5): 353-360.
[11] Arat ZM, Rübendüz M, Akgül AA. The displacement of craniofacial reference landmarks during puberty: a comparison of three superimposition metheds[J]. Angle Orthod, 2003, 73(4): 374-380.
[12] 游清玲, H?gg U. 3种X线分析头影测量方法临床应用的比较研究[J]. 上海口腔医学, 2002, 11(2): 97-100.
[13] 高益鸣, 邱蔚六, 沈国芳, 等. 正常下颌骨生长活性的核素骨显像研究[J]. 中华核医学杂志, 2000, 20(5): 213-214.
[14] 李少林, 王荣福. 核医学[M]. 北京: 人民卫生出版社, 2008: 143.
[15] Fahey FH, Abramson ZR, Padwa BL, et al. Use of 99mTc-MDP SPECT for assessment of mandibular growth: development of normal values[J]. Eur J Nucl Med Mol Imaging, 2010, 37(5): 1002-1010.
[16] Chan WL, Carolan MG, Fernandes VB, et al. Planar versus SPECT imaging in the assessment of condylar growth[J]. Nucl Med Commun, 2000, 21(3): 285-290.