用于经牙槽嵴顶上颌窦提升术的山羊模型比较

上海口腔医学 ›› 2015, Vol. 24 ›› Issue (5): 410-414.

用于经牙槽嵴顶上颌窦提升术的山羊模型比较

戴烨扬, 王德芳

上海市口腔病防治院口腔修复科,上海 200001

收稿日期:2014-09-25 修回日期:2014-12-23 出版日期:2015-10-20 发布日期:2015-11-03
通讯作者: 戴烨扬,Tel：021-63601035,E-mail：rodine@163.com
作者简介:戴烨扬（1974-）,男,硕士,主治医师

A comparative study of goat models for trans-alveolar sinus floor lift

DAI Ye-yang, WANG De-fang

Department of Prosthodontics, Shanghai Stomatological Disease Center. Shanghai 200001, China

Received:2014-09-25 Revised:2014-12-23 Online:2015-10-20 Published:2015-11-03

摘要/Abstract

摘要： 目的比较波尔山羊和上海本地山羊作为上颌后牙区经牙槽嵴顶上颌窦提升术和种植治疗模型的可行性。方法10只波尔山羊和10只本地山羊,处死后6 h内取头颅进行观察。利用CBCT扫描观察上颌骨及上颌窦的解剖,记录上颌窦侧腔的宽度和可用骨高度。取上颌窦黏膜做组织学观察。采用SPSS21.0软件包对数据进行独立样本t检验。结果山羊的上颌窦底被1个前后向骨嵴分为侧腔和近中部。波尔山羊的上颌窦侧腔宽度和可用高度均大于本地山羊。结论波尔山羊更适合做经牙槽嵴顶上颌窦提升术和牙种植的动物模型。上颌第一磨牙区中点是理想的提升与种植位点。

关键词: 动物模型, 上颌窦, 上颌窦底提升术, 牙种植体

Abstract: PURPOSE:To explore the suitability of Shanghai local goats and Boer goats as animal models for trans-alveolar sinus floor elevation and dental implants in posterior maxilla. METHODS: Ten heads of Shanghai local goats and 10 heads of Boer goats were included in this study. Their maxillary sinuses were investigated by cone-beam CT (CBCT) scan. The width and available height of lateral part of the sinus were recorded. The membrane of sinus was examined by histological analysis. Independent samples t test was performed using SPSS21.0 software package. RESULTS: Both goats had maxillary sinus similar to that of humans. The sinus floor was divided into two parts by an anteroposterior bone crest. The width and available height of the lateral part of the sinus for Bore goats were significantly higher than for Shanghai local goats (P<0.05). CONCLUSIONS: As an animal model, Boer goat is more suitable for trans-alveolar sinus floor elevation. The midpoint of the maxillary first molar is an ideal site for trans-alveolar sinus floor elevation and implantation.

Key words: Animal models, Maxillary sinus, Sinus floor elevation, Dental implant

戴烨扬, 王德芳. 用于经牙槽嵴顶上颌窦提升术的山羊模型比较[J]. 上海口腔医学, 2015, 24(5): 410-414.

DAI Ye-yang, WANG De-fang. A comparative study of goat models for trans-alveolar sinus floor lift[J]. Shanghai Journal of Stomatology, 2015, 24(5): 410-414.

参考文献

[1] Joos U, Kleinheinz J. Reconstruction of the severely resorbed (Class VI) jaws: routine or exception? [J]. J Craniomaxillofac Surg, 2000, 28(1): 1-4.
[2] Sharan A, Madjar D. Maxillary sinus pneumatization following extractions: a radiographic study [J]. Int J Oral Maxillofac Implants, 2008, 23(1):48-56.
[3] Tatum H Jr. Maxillary and sinus implant reconstruction [J]. Dent Clin North Am, 1986, 30(2): 207-229.
[4] Summers RB. The osteotome technique: Part 3-Less invasive methods of elevating the sinus floor[J]. Compendium, 1994, 15(6): 698, 700, 702-704.
[5] Cabezas-Mojón J, Barona-Dorado C, Gómez-Moreno G, et al. Meta-analytic study of implant survival following sinus augmentation [J]. Med Oral Patol Oral Cir Bucal, 2012, 17(1): e135-139.
[6] Seoane J, López-Niño J, García-Caballero L, et al. Membrane perforation in sinus floor elevation - piezoelectric device versus conventional rotary instruments for osteotomy: an experimental study [J]. Clin Implant Dent Relat Res, 2013, 15(6): 867-873.
[7] Sohn DS, Kim WS, An KM, et al. Comparative histomorphometric analysis of maxillary sinus augmentation with and without bone grafting in rabbit [J]. Implant Dent, 2010, 19(3): 259-270.
[8] Liu N, Sun F, Xu C, et al. A comparative study of dog models for osteotome sinus floor elevation and dental implants in posterior maxilla subjacent to the maxillary sinus [J]. Oral Surg Oral Med Oral Pathol Oral Radiol, 2013, 115(3): e15-20.
[9] Estaca E, Cabezas J, Usón J, et al. Maxillary sinus-floor elevation: an animal model [J]. Clin Oral Implants Res, 2008, 19(10): 1044-1048.
[10] Fenner M, Vairaktaris E, Fischer K, et al. Influence of residual alveolar bone height on osseointegration of implants in the maxilla: a pilot study [J]. Clin Oral Implants Res, 2009, 20(6): 555-559.
[11] Stelzle F, Benner KU. An animal model for sinus floor elevation with great elevation heights. Macroscopic, microscopic, radiological and micro-CT analysis: ex vivo [J]. Clin Oral Implants Res, 2010, 21(12):1370-1378.
[12] Palma VC, Magro-Filho O, de Oliveria JA, et al. Bone reformation and implant integration following maxillary sinus membrane elevation: an experimental study in primates [J]. Clin Implant Dent Relat Res, 2006, 8(1): 11-24.
[13] Wetzel AC, Stich H, Caffesse RG. Bone apposition onto oral implants in the sinus area filled with different grafting materials. A histological study in beagle dogs [J]. Clin Oral Implants Res, 1995, 6(3): 155-163.
[14] Aral A, Yalcn S, Karabuda ZC, et al. Injectable calcium phosphate cement as a graft material for maxillary sinus augmentation: an experimental pilot study [J]. Clin Oral Implants Res, 2008, 19(6): 612-617.
[15] Zou D, Guo L, Lu J, et al. Engineering of bone using porous calcium phosphate cement and bone marrow stromal cells for maxillary sinus augmentation with simultaneous implant placement in goats [J]. Tissue Eng Part A, 2012, 18(13-14): 1464-1478.
[16] López-Niño J, García-Caballero L, Gonz&#x0dbc0;&#x0dd61;lez-Mosquera A, et al. Lamb ex vivo model for training in maxillary sinus floor elevation surgery: a comparative study with human standards [J]. J Periodontol, 2012, 83(3): 354-361.
[17] Aimetti M, Massei G, Morra M, et al. Correlation between gingival phenotype and Schneiderian membrane thickness [J]. Int J Oral Maxillofac Implants, 2008, 23(6): 1128-1132.
[18] Iwai K, Arai Y, Hashimoto K, et al. Estimation of effective dose from limited cone beam X-ray CT examination [J]. Dental Radiaol, 2000, 40(6): 251-259.
[19] Marmulla R, Wörtche R, Mühling J, et al. Geometric accuracy of the NewTom 9000 Cone Beam CT[J]. Dentomaxillofac Radiol, 2005, 34(1): 28-31.