即刻种植过程中种植体周围炎动物模型的建立

上海口腔医学 ›› 2015, Vol. 24 ›› Issue (1): 37-40.

即刻种植过程中种植体周围炎动物模型的建立

沈兰花,孟玲娜,王鑫,姜辉,王珊珊

黑龙江省医院南岗院区口腔科,黑龙江哈尔滨 150001

收稿日期:2014-05-15 出版日期:2015-02-20 发布日期:2015-07-24
通讯作者: 孟玲娜,Tel：0451-88025094,E-mail:shiyu19811113@163.com
作者简介:沈兰花(1966-),女,博士,主任医师,E-mail:1347755247@qq.com
基金资助:
黑龙江省卫生厅科研课题（2010-453）

Establishment of animal model with peri-implantitis after immediate implantation in rabbits

SHEN Lan-Hua,MENG Ling-Na,WANG Xin,JIANG Hui,WANG Shan-Shan

Department of Stomatology, Nangang Branch, Heilongjiang Provincial Hospital. Haerbin 150001, Heilongjiang Province, China

Received:2014-05-15 Online:2015-02-20 Published:2015-07-24
Supported by:
Research Program from the Health Department of Heilongjiang Province (2010-453)

摘要/Abstract

摘要： 目的建立即刻种植过程中种植体周围炎动物实验模型,利用Micro-CT观察种植体周围炎发展过程中的骨缺损特性。方法在12只哈尔滨长耳白兔双侧下颌第一前牙即刻植入种植体,4周后,采用丝线拴结法在左下颌第一前牙诱发种植体周围炎,右下颌第一前牙作为对照,通过Micro-CT观察不同时期种植体周围炎导致的骨缺损状况。结果丝线拴结法可以较好地诱发出即刻种植体周围炎,随着种植体周围炎的逐渐发展,种植体与骨之间无法达到良好结合,骨缺损逐渐产生并不断扩大,最后形成典型的“V”形骨缺损。结论建立的即刻种植体周围炎动物模型简便有效,可为种植体周围炎的相关研究提供重要参考。

关键词: 种植体周围炎, 即刻种植, 动物模型, 兔

Abstract: PURPOSE: To establish animal model with peri-implantitis after immediate implantation and study bone defect characteristics by Micro-CT. METHODS: Implants were immediately planted in the first mandibular anterior tooth of 12 rabbits. Silk ligatures were placed around one side of the implants to induce peri-implantitis. Micro-CT was used to evaluate bone defect at different periods after implantation. RESULTS: Silk ligatures around the implants were effective to induce peri-implantitis. With the development of peri-implantitis, implants can not be well integrated with bone. Bone defect was gradually produced and then aggravated, and finally formed typical "V-type" bone defect. CONCLUSIONS: The establishment of animal model with peri-implantitis is simple and effective, which provides important references for relative studies in the field of peri-implantitis.

Key words: Peri-implantitis, Immediate implantation, Animal model, Rabbit

中图分类号:

R783.4

沈兰花,孟玲娜,王鑫,姜辉,王珊珊. 即刻种植过程中种植体周围炎动物模型的建立[J]. 上海口腔医学, 2015, 24(1): 37-40.

SHEN Lan-Hua,MENG Ling-Na,WANG Xin,JIANG Hui,WANG Shan-Shan. Establishment of animal model with peri-implantitis after immediate implantation in rabbits[J]. Shanghai Journal of Stomatology, 2015, 24(1): 37-40.

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