3%聚多卡醇治疗口腔黏膜低流速静脉畸形的临床效果评价

doi:10.19439/j.sjos.2025.06.016

上海口腔医学 ›› 2025, Vol. 34 ›› Issue (6): 647-650.doi: 10.19439/j.sjos.2025.06.016

3%聚多卡醇治疗口腔黏膜低流速静脉畸形的临床效果评价

刘爽, 孙宁宁, 刘敏达, 代炜, 薛雷, 张恩礁

中国医科大学附属口腔医院口腔颌面外科, 辽宁沈阳 110002

收稿日期:2025-01-23 修回日期:2025-02-20 发布日期:2025-12-30
通讯作者: 张恩礁,E-mail: EnjiaoZhangCMU@163.com
作者简介:刘爽（1984-）,女,博士,主治医师,E-mail: liushuang_cmu@163.com
基金资助:
中国医科大学附属口腔医院院级“三新技术”（L101593-2024-09）

Evaluation of the clinical efficacy of 3% polydocaol in the treatment of low-flow oral mucosal venous malformation

Liu Shuang, Sun Ningning, Liu Minda, Dai Wei, Xue Lei, Zhang Enjiao

Department of Oral and Maxillofacial Surgery, Affiliated Stomatological Hospital of China Medical University. Shenyang 110002, Liaoning Province, China

Received:2025-01-23 Revised:2025-02-20 Published:2025-12-30

摘要/Abstract

摘要： 目的:探讨3%聚多卡醇治疗口腔黏膜低流速静脉畸形的临床效果。方法:选择2024年1月—12月中国医科大学附属口腔医院口腔颌面外科门诊收治的口腔黏膜低流速静脉畸形患者62例,采用3%聚多卡醇泡沫硬化剂治疗,随访1~12个月,通过疗效等级评价、患者主观评价及治疗前后照片对比评估治疗效果。结果:62例患者中,治愈52例（83.87%）,显效8例,有效2例,总有效率为100%。治疗次数1~3 次,平均1.4次。视觉模拟评分（visual analogue scale,VAS）显示术后即刻疼痛3~8 分,1个月后降至0~1分。8例患者术后出现不良反应,1个月后均恢复正常。结论:3%聚多卡醇治疗口腔黏膜静脉畸形是一种安全、有效、副作用小的治疗方法。

关键词: 静脉畸形, 聚多卡醇, 硬化治疗, 口腔黏膜

Abstract: PURPOSE: To investigate the clinical efficacy of 3% polidocanol in the treatment of low-flow venous malformations of the oral mucosa. METHODS: A total of 62 patients with low-flow venous malformations of the oral mucosa admitted to the Department of Oral and Maxillofacial Surgery, Affiliated Stomatological Hospital of China Medical University from January to December 2024 were selected. All patients were treated with 3% polidocanol foam sclerotherapy and followed up for 1 to 12 months. The therapeutic effects were evaluated through grade assessment, subjective evaluation by patients, and comparison of photos before and after treatment. RESULTS: Among the 62 patients, 52 were cured (83.87%), 8 showed remarkbally improved, and 2 were improved, with a total effective rate of 100%. The number of treatments ranged from 1 to 3 times, with an average of 1.4 times. Visual analogue scale(VAS) of pain showed that immediate postoperative pain score was 3-8 points, which decreased to 0-1 points after 1 month. Adverse reactions occurred in 8 patients postoperatively, all of them returned to normal after 1 month. CONCLUSIONS: 3% polidocanol is a safe, effective, and low-side-effect treatment for venous malformations of the oral mucosa.

Key words: Venous malformation, Polydocaol, Sclerotherapy, Oral mucosa

中图分类号:

R782.2

刘爽, 孙宁宁, 刘敏达, 代炜, 薛雷, 张恩礁. 3%聚多卡醇治疗口腔黏膜低流速静脉畸形的临床效果评价[J]. 上海口腔医学, 2025, 34(6): 647-650.

Liu Shuang, Sun Ningning, Liu Minda, Dai Wei, Xue Lei, Zhang Enjiao. Evaluation of the clinical efficacy of 3% polydocaol in the treatment of low-flow oral mucosal venous malformation[J]. Shanghai Journal of Stomatology, 2025, 34(6): 647-650.

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3%聚多卡醇治疗口腔黏膜低流速静脉畸形的临床效果评价

Evaluation of the clinical efficacy of 3% polydocaol in the treatment of low-flow oral mucosal venous malformation

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