氟离子导入预防儿童龋齿的效果及影响因素分析

doi:10.19439/j.sjos.2025.04.012

上海口腔医学 ›› 2025, Vol. 34 ›› Issue (4): 409-413.doi: 10.19439/j.sjos.2025.04.012

氟离子导入预防儿童龋齿的效果及影响因素分析

郭晓瑨¹, 卢茜², 张凯驰², 郭晓琳²

1.首都医科大学附属北京友谊医院口腔科, 北京 101100;
2.秦皇岛市妇幼保健院口腔科, 河北秦皇岛 066000

收稿日期:2025-03-03 修回日期:2025-04-29 出版日期:2025-08-25 发布日期:2025-08-26
通讯作者: 郭晓琳,E-mail：975767991@qq.com
作者简介:郭晓瑨（1989-）,女,硕士,主治医师,E-mail：18513392687@163.com
基金资助:
秦皇岛市科学技术研究与发展计划（202301A027）

Analysis of the effect and influencing factors of fluoride iontophoresis in preventing dental caries in children

Guo Xiaojin¹, Lu Qian², Zhang Kaichi², Guo Xiaolin²

1. Department of Stomatology, Beijing Friendship Hospital, Capital Medical University. Beijing 101100;
2. Department of Stomatology, Qinhuangdao City Maternal and Child Health Care Hospital. Qinhuangdao 066000, Heibei Province, China

Received:2025-03-03 Revised:2025-04-29 Online:2025-08-25 Published:2025-08-26

摘要/Abstract

摘要： 目的：探讨氟离子导入预防儿童龋齿效果、唾液氟代谢特征及影响因素。方法：选择2022年4月—2023年10月500例行口腔检查的儿童,按照随机数字表法分为试验组及对照组,每组各250例。对照组进行常规预防,试验组进行氟离子导入预防。比较两组干预前及干预后12个月防龋效果、唾液氟浓度及干预12个月后的患龋率,按照是否患龋分为患龋组（258例）及无龋组（242例）,对比两组一般资料,采用多元logistic回归分析儿童患龋的影响因素。结果：干预12个月后,试验组龋失补（decayed, missing and filled teeth,DMFT）指数和显著性龋均指数（significant caries index,SiC）显著低于对照组（P<0.05）。干预30 min、2 h、4 h、6 h及2 d后,试验组唾液中氟浓度显著高于对照组（P<0.05）。干预后12个月,试验组患龋率显著低于对照组（P<0.05）。单因素分析结果显示,年龄、断奶年龄、甜食食用频率、夜间进食频率、开始刷牙年龄、刷牙频率、牙膏是否含氟、是否定期检查及干预后游离氟浓度是儿童患龋的影响因素（P<0.05）。多因素logistic回归分析结果显示,年龄大及断奶年龄大是儿童患龋的独立危险因素（P<0.05）,甜食食用频率<3次/周、夜间进食频率<5次/周、牙膏含氟及定期口腔检查是儿童患龋的独立保护因素（P<0.05）。结论：氟离子导入能显著降低儿童龋发生率,提高唾液中氟浓度,并受多种因素影响。

关键词: 氟离子导入, 龋齿, 唾液氟浓度, 龋失补指数, 影响因素

Abstract: PURPOSE: To explore the effect of fluoride iontophoresis in preventing dental caries in children, characteristics of saliva fluoride metabolism and influencing factors. METHODS: A total of 500 children who underwent oral examinations from April 2022 to October 2023 were selected and divided into experimental group and control group according to the random number table method, with 250 children in each group. The control group received routine prevention, while the experimental group received fluoride iontophoresis prevention. The caries prevention effects, salivary fluoride concentrations and caries prevalence after 12 months of intervention were compared between the two groups before intervention and 12 months after intervention, according to whether they had caries or not, they were divided into caries group (n=258) and non-caries group (n=242). The general data of the two groups were compared, and the influencing factors of caries in children were analyzed by multivariate logistic regression. RESULTS: Twelve months after intervention, the decayed, missing and filled teeth (DMFT) index and significant caries index (SiC) in the experimental group were significantly lower than those in the control group (P<0.05). At 30 minutes, 2 hours, 4 hours, 6 hours, and 2 days after intervention, the salivary fluoride concentration in the experimental group was significantly higher than that in the control group (P<0.05). Twelve months after intervention, the caries incidence rate in the experimental group was significantly lower than that in the control group (P<0.05). The results of univariate analysis showed that age, weaning age, frequency of sweet food consumption, frequency of night eating, age of starting to brush teeth, brushing frequency, toothpaste with or without fluoride, regular check-ups and the concentration of free fluoride after intervention were the influencing factors of dental caries in children (P<0.05). The results of multivariate logistic regression analysis showed that older age and older weaning age were independent risk factors for dental caries in children (P<0.05), while the frequency of sweet food consumption<3 times per week, the frequency of nocturnal eating<5 times per week, fluoride content in toothpaste and regular oral examinations were independent protective factors for dental caries in children (P<0.05). CONCLUSIONS: Fluoride iontophoresis can significantly reduce the incidence of dental caries in children, increasing the fluoride concentration in saliva, affected by multiple factors.

Key words: Fluoride iontophoresis, Dental caries, Salivary fluoride concentration, Decayed, missing and filled teeth index, DMFT, Influencing factors

中图分类号:

R780.1

郭晓瑨, 卢茜, 张凯驰, 郭晓琳. 氟离子导入预防儿童龋齿的效果及影响因素分析[J]. 上海口腔医学, 2025, 34(4): 409-413.

Guo Xiaojin, Lu Qian, Zhang Kaichi, Guo Xiaolin. Analysis of the effect and influencing factors of fluoride iontophoresis in preventing dental caries in children[J]. Shanghai Journal of Stomatology, 2025, 34(4): 409-413.

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氟离子导入预防儿童龋齿的效果及影响因素分析

Analysis of the effect and influencing factors of fluoride iontophoresis in preventing dental caries in children

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