Abstract: PURPOSE: To investigate the effect of absorbable protein collagen suture on wound healing and inflammatory factors in gingival crevicular fluid in oral implant surgery. METHODS: A total of 128 patients with oral implants admitted to the People's Hospital of Dazu District, Chongqing City from March 2018 to October 2019 were selected and divided into the absorbable group (sutured with absorbable collagen suture) and the conventional group (sutured with conventional suture) using a random number table, with 64 cases in each group. The incision healing time, postoperative pain degree of patients, incision healing grade, incidence of complications, level of tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and interleukin-8 (IL-8) in gingival crevicular fluid of the two groups of patients were compared. Results: The incision healing time of patients in the absorbable group was significantly shorter than that in the conventional group (P<0.05); at 1 and 2 days after operation, the degree of pain in the absorbable group was significantly less than that in the conventional group (P<0.05). The healing rate of grade A incision in the absorbable group was 96.88%, and that of grade B incision was 3.13%; in the conventional group, the healing rate of grade A incision was 81.25%, grade B incision was 17.19%, and grade C incision was 1.56%, the absorbable group was significantly better than the conventional group(P<0.05). Before operation, there was no significant difference in the levels of TNF-α, IL-6 and IL-8 in the gingival crevicular fluid between the absorbable group and the conventional group (P>0.05). Three days after operation, the levels of TNF-α, IL-6 and IL-8 in the gingival crevicular fluid of the absorbable group were significantly lower than those of the conventional group (P<0.05). The incidence of complications in the absorbable group (6.25%) was significantly lower than that in the conventional group (18.75%). CONCLUSIONS: The use of absorbable collagen suture during oral implant surgery is conducive to incision healing, reducing postoperative pain and inflammatory reaction.

Key words: Absorbable, Collagen suture, Implant repair, Gingival crevicular fluid, Inflammatory factors