Abstract: PURPOSE: To evaluate and compare the efficacy and safety of Carisolv minimally invasive gel caries removal technique combined with penetrating and composite resins in the treatment of caries in deciduous teeth. METHODS: A total of 218 children treated for deciduous tooth caries in Stomatology Hospital of Hebei Medical University from January 2019 to January 2024 were selected and divided into control group (n=109) and experimental group (n=109) by random number table method. After caries removal with Carisolv minimally invasive gel, the control group was filled with osmotic resin, and the experimental group was filled with composite resin. Sulcus bleeding index(SBI), gingival index(GI), plaque index(PLI), chewing function and levels of periodontal inflammatory factors were compared between the two groups before and after treatment. Results: The operation time and oral function recovery time in the experimental group were (4.12±0.58) min and (29.12±3.02) d, respectively, which were significantly shorter than those in the control group (6.53±1.02) min and (36.54±3.52) d (P<0.05). The differences of SBI, GI and PLI in the experimental group were significantly higher than those in the control group (P<0.05). The changes of serum TNF-α, IL-6, and IL-8 levels in the experimental group were significantly higher than those in the control group (P<0.05). The difference in resting masseter muscle electromyographic activity in the experimental group was significantly lower than that in the control group, the differences in resting temporal muscle electromyographic activity, maximal clenching masseter muscle electromyographic activity and maximal clenching temporal muscle electromyographic activity were significantly higher than those in the control group (P<0.05). The numbers of cases with moderate to severe pain were significantly lower in the experimental group (P<0.05). The overall treatment efficacy rate in the experimental group was 96.3%, significantly higher than that in the control group (83.5%, P<0.05). The incidence of adverse reactions was significantly lower in the experimental group (P<0.05). CONCLUSIONS: Carisolv minimally invasive gel combined with composite resin for primary tooth caries can significantly shorten the treatment and oral function recovery time, improve the periodontal health index after treatment, reduce pain and adverse reactions, with a higher overall effective rate.

Key words: Primary dental caries, Carisolv minimally invasive gel, Osmotic resin, Composite resin