上海口腔医学

上海口腔医学 ›› 2020, Vol. 29 ›› Issue (2): 213-216.doi: 10.19439/j.sjos.2020.02.019

• 论著 • 上一篇    下一篇

自体牙本质颗粒结合富血小板纤维蛋白膜治疗93例下颌第一磨牙根分叉病变效果评价

吴峥嵘, 左园林, 李朝晖   

  1. 广州市花都区妇幼保健院·胡忠医院 口腔科,广东 广州 510800
  • 收稿日期:2019-04-12 修回日期:2019-07-08 出版日期:2020-04-25 发布日期:2020-04-30
  • 通讯作者: 李朝晖,E-mail:zuo416@163.com
  • 作者简介:吴峥嵘(1981-),本科,主治医师,E-mail:oppa744@126.com

Evaluation of 93 cases of mandibular first molar root bifurcation lesions treated with autologous dentin Granules combined with platelet-rich fibrin membrane

WU Zheng-rong, ZUO Yuan-lin, LI Chao-hui   

  1. Department of Stomatology, Maternal and Child Health Care Hospital of Huadu District. Guangzhou 510800, Guangdong Province, China
  • Received:2019-04-12 Revised:2019-07-08 Online:2020-04-25 Published:2020-04-30

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摘要： 目的 探讨自体牙本质颗粒结合富血小板纤维蛋白膜(platelet-rich fibrin membrane,PRF)治疗下颌第一磨牙根分叉病变的疗效。方法 选择2016年2月—2017年10月花都区妇幼保健院口腔科门诊诊治的93例(93颗牙)下颌第一磨牙根分叉病变患者,随机分为2组,实验组(46例、46颗牙)采用自体牙本质颗粒结合富血小板纤维蛋白膜治疗,对照组(47例、47颗牙)采用Bio-Oss植入骨缺损区,覆盖胶原膜治疗,术后1、3、6、12个月复查,比较2组手术成功率,治疗前、后牙周袋深度(periodontal pocket,PD)、附着丧失(loss of attachment,AL)、根分叉水平探入深度(depth of penetration of the root bifurcation,HPD)、根分叉区骨密度的差异。采用SPSS 25.0软件包对数据进行统计学分析。结果 实验组手术成功45颗(97.83%),对照组40颗(85.11%),2组相比差异显著(P<0.05)。2组治疗后PD、AL、HPD显著下降(P<0.05),MGVs值逐渐增高。实验组治疗后1个月与治疗前MGVs值差异无统计学意义(P>0.05),其余各时间点MGVs值显著高于对照组(P<0.05);实验组治疗后各时间点PD、AL、HPD显著低于对照组(P<0.05),MGVs值显著高于对照组(P<0.05);2组术后并发症发生率无显著差异(4.35%∶6.38%, χ2=0.189,P>0.05)。结论 自体牙本质颗粒结合富血小板纤维蛋白膜治疗下颌第一磨牙根分叉病变效果显著,值得临床推广。

关键词: 自体牙本质颗粒, 富血小板纤维蛋白膜, 下颌第一磨牙, 根分叉病变

Abstract: PURPOSE: To investigate the efficacy of autologous dentin particles combined with platelet-rich fibrin membrane (PRF) in the treatment of root bifurcation lesions of mandibular first molar. METHODS: Ninety-three patients (93 teeth) with mandibular first molar root bifurcation lesions were selected from our department from February 2016 to October 2017. They were randomly divided into 2 groups. Forty-six patients with 46 teeth in the experimental group underwent autologous dentin particles combined with platelet-rich fibrin membrane, while patents in the control group (47 patients with 47 teeth) were treated with Bio-Oss implanted in the bone defect area covered with collagen membrane. The patients were revisted at 1, 3, 6 and 12 months after operation. The success rate of the operation group, the depth of periodontal pocket (PD), the loss of attachment (AL), the depth of penetration of the root bifurcation (HPD), and the bone density of the root bifurcation area before and after treatment. The data were recorded and compared with SPSS25.0 software package. RESULTS: The success rate was 97.83%(45/46) in the experimental group, 85.11%(40/47) in the control group, the difference between the two groups was significant(P<0.05). After treatment, PD, AL and HPD decreased significantly (P<0.05), and MGVs increased gradually. There was no significant difference in MGVs before treatment and 1 month after treatment in the experimental group (P>0.05). MGVs at other time points were significantly higher than those of the control group (P<0.05). PD, AL and HPD of the experimental group were lower significantly than the control group at each time point after treatment (P<0.05), and MGVs value was significantly higher than the control group (P<0.05). There was no significant difference in the incidence of complications(4.35% vs 6.38%, χ2=0.189, P>0.05). CONCLUSIONS: Autologous dentin particles combined with platelet-rich fibrin membrane is effective for the treatment of root bifurcation lesions of mandibular first molar, which is worthy of wide application.

Key words: Autologous dentin particles, Platelet-rich fibrin membrane, Mandibular first molar, Root bifurcation lesion

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