纯钛在仿真蛋白环境中腐蚀性能的电化学阻抗谱分析

上海口腔医学 ›› 2014, Vol. 23 ›› Issue (5): 543-546.

纯钛在仿真蛋白环境中腐蚀性能的电化学阻抗谱分析

吕继新¹, 翁维民²

1.浙江横店集团医院口腔科,浙江东阳 322118; 2.上海交通大学医学院附属第九人民医院·口腔医学院口腔修复科,上海市口腔医学重点实验室,上海 200011

收稿日期:2014-04-29 修回日期:2014-07-09 出版日期:2014-10-20 发布日期:2015-02-04
通讯作者: 翁维民,Tel:021-23271699,E-mail:wengweimin31@126.com
作者简介:吕继新（1973-）,男,学士,副主任医师,Tel：0579-86586933,E-mail:zjdyljx@126.com
基金资助:
上海市科学技术委员会资助项目(08DZ2271100)

Electrochemical impedance spectroscopic study of titanium in physiological environment with blood-serum protein

LV Ji-xin¹, WENG Wei-min²

1.Department of Stomatology, Hengdian Group Hospital. Dongyong 322118, Zhejiang Province; 2.Department of Prosthodontics, Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology. Shanghai 200011, China

Received:2014-04-29 Revised:2014-07-09 Online:2014-10-20 Published:2015-02-04
Supported by:
; Supported by Research Fund of Science and Technology Committee of Shanghai Municipality (08DZ2271100)

摘要/Abstract

摘要： 目的在高仿真环境中,采用电化学阻抗法分析纯钛种植材料的腐蚀性能。方法以PBS液为对照组,细胞培养液为实验组,采用电化学分析仪测试钛在含血清蛋白体系中的电化学阻抗谱,利用EIS-Nyquist图、EIS-Bode图及等效电路的拟合分析,研究血清蛋白对钛的抗腐蚀性能的影响,采用SPSS11.0软件包对数据进行统计学分析。结果纯钛材料在细胞培养液中的氧化膜阻抗值（24.8±3.9）×10⁵ Ω显著大于在PBS液中的阻抗值（6.7±0.8）×10⁵ Ω（P<0.05）。纯钛在PBS中低频区的相位角约为55°,而在细胞培养液中低频区的相位角约为75°。结论机体环境中的血清蛋白能够影响钛金属在体液中的腐蚀性能。

关键词: 钛, 腐蚀, 电化学阻抗, 血清蛋白

Abstract: PURPOSE: Electrochemical impedance spectroscopy (EIS) was employed to study the corrosion behaviour of titanium in dummy environment with blood-serum protein. METHODS: EIS of titanium in PBS and cell culture fluid was acquired by advanced electrochemical system. The characteristic of EIS-Nyquist and EIS-Bode were investigated and the equivalent circuit was used to analyze the EIS results. The data was analyzed using SPSS 11.0 software package. RESULTS: The corrosion resistance of the titanium in cell culture fluid was significantly higher than that in PBS (P<0.05). The phase angle of TiO₂-based passive film at low frequency decreased to 55° when titanium was in PBS, but 75° when in cell culture fluid. CONCLUSIONS: The blood-serum protein plays an important role in the corrosion behaviour of titanium in physiological environment.

Key words: Titanium, Corrosion, Electrochemical impedance spectroscopy, Blood-serum protein

吕继新, 翁维民. 纯钛在仿真蛋白环境中腐蚀性能的电化学阻抗谱分析[J]. 上海口腔医学, 2014, 23(5): 543-546.

LV Ji-xin, WENG Wei-min. Electrochemical impedance spectroscopic study of titanium in physiological environment with blood-serum protein[J]. Shanghai Journal of Stomatology, 2014, 23(5): 543-546.

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