Nd:YAG激光和Er:YAG激光治疗2型糖尿病患者种植体周围炎的短期效果评价

doi:10.19439/j.sjos.2026.01.009

摘要/Abstract

摘要： 目的评价Nd:YAG激光和Er:YAG激光治疗2型糖尿病患者种植体周围炎的短期效果。方法选择2021年2月—2024年2月收治的2型糖尿病种植体周围炎患者97例,采用随机数字表法分为A组（48例,Nd:YAG激光）和B组（49例,Er:YAG激光）。对比两组患者治疗前后的牙周指标、炎性因子水平、骨吸收程度、龈沟液细菌含量、血糖水平、生活质量评分及疗效。结果治疗后,两组龈沟出血指数（sulcus bleeding index,SBI）、菌斑指数（plaque index,PLI）和牙周探诊深度（probing depth,PD）显著降低,且A组SBI、PLI和PD均显著低于B组（P<0.05）。治疗后,两组近、远中边缘骨吸收显著降低,且A组显著低于B组（P<0.05）。两组炎性因子水平治疗后显著降低,A组白细胞介素6（IL-6）、肿瘤坏死因子α（tumor necrosis factor α,TNF-α）和基质金属蛋白酶8(matrix metalloproteinase- 8,MMP-8）水平均显著低于B组（P<0.05）。两组龈沟液细菌含量治疗后显著降低,且A组显著低于B组（P<0.05）。治疗前、后两组患者血糖水平相比无显著差异（P>0.05）。治疗后,两组生活质量评分显著升高,A组躯体功能、心理功能及总分均显著高于B组（P<0.05）。两组治疗总有效率相比,无显著差异（P>0.05）。结论 Nd:YAG激光治疗2型糖尿病患者种植体周围炎能有效改善牙周情况,减少骨吸收,降低炎性因子水平及龈沟液细菌含量,提高生活质量。

关键词: Nd:YAG激光, Er:YAG激光, 2型糖尿病, 种植体周围炎, 牙周指标

Abstract: PURPOSE: To evaluate the short-term efficacy of Nd:YAG laser and Er:YAG laser in the treatment of peri-implantitis in patients with type 2 diabetes. METHODS: A total of 97 patients with peri-implantitis of type 2 diabetes mellitus who were admitted from February 2021 to February 2024 were selected and divided into group A (n=48, Nd:YAG laser) and group B (n=49, Er:YAG laser) by random number table method.The periodontal indicators, levels of inflammatory factors, degree of bone resorption, bacterial content in gingival crevicular fluid, blood glucose levels, quality of life scores and therapeutic effects of the two groups of patients before and after treatment were compared. RESULTS: After treatment, the sulcus bleeding index (SBI), plaque index (PLI) and probing depth (PD) in group A and B decreased significantly. SBI, PLI and PD in group A were significantly lower than those in group B(P<0.05). After treatment, the bone resorption at the proximal and distal margins in groups A and B decreased significantly. The bone resorption at the proximal and distal margins in group A was significantly lower than that in group B(P<0.05). The levels of inflammatory factors in the two groups decreased significantly after treatment. IL-6, tumor necrosis factor α(TNF-α) and matrix metalloproteinase-8 (MMP-8) of group A were significantly lower than those of group B (P<0.05). The bacterial content of gingival crevicular fluid in both groups decreased significantly after treatment. Group A was significantly lower than that in group B (P<0.05). There was no significant difference in blood glucose levels between the two groups of patients before and after treatment(P>0.05). After treatment, the quality of life scores of both groups increased significantly. The physical function, psychological function and total score of group A were significantly higher than those of group B(P<0.05). There was no significant difference in the total effective rate of treatment between the two groups(P>0.05). CONCLUSIONS: Nd:YAG laser treatment for peri-implantitis in patients with type 2 diabetes can effectively improve periodontal conditions, reduce bone resorption, lower the levels of inflammatory factors and the bacterial content in gingival crevicular fluid, and enhance the quality of life.

Key words: Nd:YAG laser, Er:YAG laser, Type 2 diabetes, Peri-implantitis, Periodontal indices

中图分类号:

R781.05

孙斌, 王苹. Nd:YAG激光和Er:YAG激光治疗2型糖尿病患者种植体周围炎的短期效果评价[J]. 上海口腔医学, 2026, 35(1): 54-59.

Sun Bin, Wang Ping. Short-term effect of Nd:YAG and Er:YAG lasers in the treatment of peri-implantitis in patients with type 2 diabetes[J]. Shanghai Journal of Stomatology, 2026, 35(1): 54-59.

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