Abstract: PURPOSE: To explore the impact of minimally invasive circumferential resection on inflammatory response and alveolar crest resorption in patients with dental defect implantation. METHODS: A total of 198 patients who received dental implantation in Lishui Hospital of Traditional Chinese Medicine from June 2021 to June 2023 were selected and divided into minimally invasive group (n=100) and traditional group (n=98) according to treatment methods. Minimally invasive surgery was performed in the minimally invasive group and traditional flap surgery was performed in the traditional group.Surgical related indicators, levels of inflammatory factors, pain mediators, alveolar crest bone resorption, implant loosening, quality of life and complication rates were compared between the two groups. SPSS 27.0 software package was used for statistical analysis. RESULTS: The surgery time, postoperative VAS scores and postoperative pain reaction time in the minimally invasive group were significantly lower than those in the traditional group(P<0.05). In the minimally invasive group, the concentrations of IL-8, TNF-α, INF-γ,serum amyloid A(SAA), substance P(SP), calcitonin gene-related peptide(CGRP) and 5-hydroxytryptamine(5-HT) were significantly lower than the traditional group (P<0.05). The amount of alveolar crest bone absorption in minimally invasive group was significantly lower than that in the traditional group(P<0.05). There was no significant differences in implant loosening and retention rates between the two groups(P>0.05). OHIP-14 scores across all dimensions in the minimally invasive group were significantly lower than in the traditional group (P<0.05). There was no significant difference in complication rate between the minimally invasive group and the traditional group (P<0.05). CONCLUSIONS: Compared with the traditional surgery, minimally invasive circumferential surgery has better performance in reducing operation time, postoperative inflammatory factors and pain mediators, alveolar crest and parietal bone absorption and improving oral health, which can be widely used in dental implantation.

Key words: Dentition defect, Implantation, Minimally invasive circumferential incision technique, Inflammatory response, Alveolar crest bone resorption