Abstract: PURPOSE: To compare the clinical efficacy of CAD/CAM all-ceramic inlay and polymerid porcelain inlay in restoring Class Ⅱ cavity of posterior teeth. METHODS: Ninety-seven patients with 100 posterior teeth of ClassⅡ cavity were recruited in this randomized control trial; Among them, 50 patients were grouped into CAD/CAM all-ceramic inlays and 47 patients were grouped into Ceramage polymerid porcelain inlay. According to the modified USPHS criteria, the incidence of postoperative sensitivity, prosthesis fracture, prosthesis falling off, and edge coloration were evaluated 12 months and 24 months after restoration. X² test and Wilcoxon rank sum test were used for statistical analysis using SPSS 13.0 software package. RESULTS: Restoration in the 2 groups were successful, there was no significant difference at 12 months (P>0.05). Postoperative sensitivity and the incidence of prosthesis falling off in both groups were not significantly different (P>0.05); however, the number of prosthesis fracture of the polymerid porcelain was lower than that of the CAD/CAM all-ceramic inlays (P<0.05). The incidence of edge coloration of CAD/CAM all-ceramic inlays was lower than that of the polymerid porcelain at 24-month follow-up (P<0.05). CONCLUSIONS: Restoration with polymerid porcelain is more likely to have a higher success rate than those with CAD/CAM all-ceramic inlays. Patients undergoing CAD/CAM all-ceramic inlays have a lower incidence of edge coloration, compared with those undergoing polymerid porcelain.

Key words: Inlay, Computer aided design /computer aided manufacturing, Class II cavity