Expression of receptor activator of nuclear factor-κB ligand in keratocystic odontogenic tumor before and after decompression

doi:10.19439/j.sjos.2017.04.017

Shanghai Journal of Stomatology ›› 2017, Vol. 26 ›› Issue (4): 434-436.doi: 10.19439/j.sjos.2017.04.017

• Orignal Article • Previous Articles Next Articles

Expression of receptor activator of nuclear factor-κB ligand in keratocystic odontogenic tumor before and after decompression

ZHANG Bo¹, YE Wen-cheng¹, LI Ying¹, ZHOU Xin-mu², MAO Wei-bo², ZHU Yi-ling²

1.Department of Stomatology,
2.Department of Pathology, Lishui Hospital of Zhejiang University, Lishui Central Hospital. Lishui 323000, Zhejiang Province, China

Received:2017-01-15 Revised:2017-04-06 Online:2017-08-25 Published:2017-09-01

Abstract

Abstract: To investigate the expression of receptor activator of nuclear factor-κB ligand (RANKL) in keratocystic odontogenic tumor (KCOT) before and after decompression. METHODS: Twenty two pairs of paraffin-embeded tissue specimens of KCOT were collected and subjected to immunohistochemical analysis of RANKL.The data were analyzed with SPSS17.0 software package for paired t test. RESULTS: RANKL positive cells were observed in the preoperative KCOT epithelium. The expression of RANKL was down-regulated after decompression(P<0.05).CONCLUSIONS: Decrease of RANKL expression after decompression may facilitate the lining epithelium of KCOT transforming to normal oral mucosal epithelium.

Key words: Receptor activator of nuclear factor-κ, B ligand, Keratocystic odontogenic tumor, Decompression

CLC Number:

R739.82

ZHANG Bo, YE Wen-cheng, LI Ying, ZHOU Xin-mu, MAO Wei-bo, ZHU Yi-ling. Expression of receptor activator of nuclear factor-κB ligand in keratocystic odontogenic tumor before and after decompression[J]. Shanghai Journal of Stomatology, 2017, 26(4): 434-436.

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Expression of receptor activator of nuclear factor-κB ligand in keratocystic odontogenic tumor before and after decompression

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