Shanghai Journal of Stomatology ›› 2026, Vol. 35 ›› Issue (1): 54-59.doi: 10.19439/j.sjos.2026.01.009

• Original Articles • Previous Articles     Next Articles

Short-term effect of Nd:YAG and Er:YAG lasers in the treatment of peri-implantitis in patients with type 2 diabetes

Sun Bin1, Wang Ping2   

  1. 1. Department of Stomatology, Wuxi Second People's Hospital. Wuxi 214000;
    2. Department of Periodontics, Wuxi Stomatological Hospital. Wuxi 214000, Jiangsu Province, China
  • Received:2025-03-24 Revised:2025-05-13 Online:2026-03-12 Published:2026-03-12

Abstract: PURPOSE: To evaluate the short-term efficacy of Nd:YAG laser and Er:YAG laser in the treatment of peri-implantitis in patients with type 2 diabetes. METHODS: A total of 97 patients with peri-implantitis of type 2 diabetes mellitus who were admitted from February 2021 to February 2024 were selected and divided into group A (n=48, Nd:YAG laser) and group B (n=49, Er:YAG laser) by random number table method.The periodontal indicators, levels of inflammatory factors, degree of bone resorption, bacterial content in gingival crevicular fluid, blood glucose levels, quality of life scores and therapeutic effects of the two groups of patients before and after treatment were compared. RESULTS: After treatment, the sulcus bleeding index (SBI), plaque index (PLI) and probing depth (PD) in group A and B decreased significantly. SBI, PLI and PD in group A were significantly lower than those in group B(P<0.05). After treatment, the bone resorption at the proximal and distal margins in groups A and B decreased significantly. The bone resorption at the proximal and distal margins in group A was significantly lower than that in group B(P<0.05). The levels of inflammatory factors in the two groups decreased significantly after treatment. IL-6, tumor necrosis factor α(TNF-α) and matrix metalloproteinase-8 (MMP-8) of group A were significantly lower than those of group B (P<0.05). The bacterial content of gingival crevicular fluid in both groups decreased significantly after treatment. Group A was significantly lower than that in group B (P<0.05). There was no significant difference in blood glucose levels between the two groups of patients before and after treatment(P>0.05). After treatment, the quality of life scores of both groups increased significantly. The physical function, psychological function and total score of group A were significantly higher than those of group B(P<0.05). There was no significant difference in the total effective rate of treatment between the two groups(P>0.05). CONCLUSIONS: Nd:YAG laser treatment for peri-implantitis in patients with type 2 diabetes can effectively improve periodontal conditions, reduce bone resorption, lower the levels of inflammatory factors and the bacterial content in gingival crevicular fluid, and enhance the quality of life.

Key words: Nd:YAG laser, Er:YAG laser, Type 2 diabetes, Peri-implantitis, Periodontal indices

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