添加纳米聚磷腈对聚氨酯材料微生物黏附性能的影响

上海口腔医学 ›› 2014, Vol. 23 ›› Issue (4): 419-422.

添加纳米聚磷腈对聚氨酯材料微生物黏附性能的影响

孔方圆¹, 郑元俐², 李静²

1.上海交通大学医学院附属第九人民医院·口腔医学院牙体牙髓病科,上海 200011
2.口腔修复科,上海市口腔医学重点实验室,上海 200011

收稿日期:2013-09-29 出版日期:2014-08-20 发布日期:2014-10-20
通讯作者: 郑元俐,E-mail:zhengyuanli@yahoo.com
作者简介:孔方圆(1985-), 女, 硕士, 住院医师, E-mail:kongfangyuan2005@126.com
基金资助:
上海市科学技术委员会资助项目(0941195470)

The effect of additional polyphosphazene nanotubes in polyurethane composites on microorganisms adhesion

KONG Fang-yuan¹, ZHENG Yuan-li², LI Jing²

1.Department of Endodontics, Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine. Shanghai 200011, China
2.Department of Prosthodontics, Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology. Shanghai 200011, China

Received:2013-09-29 Online:2014-08-20 Published:2014-10-20
Supported by:
Supported by Research Fund of Science and Technology Committee of Shanghai Municipality (0941195470).

摘要/Abstract

摘要： 目的:观察纯聚氨酯材料(PU)、含1%和5%纳米聚磷腈的聚氨酯材料(PZS-1%、PZS-5%)表面白念菌和变形链球菌黏附情况。方法:测定3种材料(PU、PZS-1%、PZS-5%)表面粗糙度,并将其分别于白念菌和变链球菌菌液中进行黏附实验,分析材料表面微生物的黏附情况。采用SAS8.02软件包对数据进行统计学分析。结果:PU、PZS-1%和PZS-5%材料的表面粗糙度由大到小依次为PU>PZS-1%>PZS-5%(P<0.001);白念菌和变链球菌黏附实验中,黏附微生物量从多到少依次为PU>PZS-1%>PZS-5%(P<0.001)。结论:添加不同比例的纳米聚磷腈,对聚氨酯材料微生物黏附性能有一定影响。

关键词: 聚氨酯, 聚磷腈, 白念菌, 变形链球菌

Abstract: PURPOSE: To investigate Candida albicans and Streptococcus mutans adhesion to 3 polyurethane composites [pure polyurethane (PU), 1% polyphosphazene-containing polyurethane (PZS-1%) and 5% polyphosphazene-containing polyurethane (PZS-5%)]. METHODS: Two kinds of microorganism suspension were incubated with the specimens under certain culture conditions and the roughness of 3 materials were determined before adhesion tests. Microorganism attached to the specimen were then observed under optical microscope, and viable micro-organisms adhered to the specimen were then counted and removed. The data was analyzed with SAS 8.02 softwaree package. RESULTS: PU has the roughest surface followed by PZS-1% and PZS-5%. Most amounts of cell adhesion were observed in PU followed by PZS-1% and least amounts were found in PZS-5%. CONCLUSIONS: The increase of polyphosphazene nanotubes in polyurethane composites may have an effect on cell adhesion. Surface roughness of the materials may be one of the factors.

Key words: Polyurethane, Polyphosphazene, Candida albicans, Streptococcus mutans

中图分类号:

R783.1

孔方圆, 郑元俐, 李静. 添加纳米聚磷腈对聚氨酯材料微生物黏附性能的影响[J]. 上海口腔医学, 2014, 23(4): 419-422.

KONG Fang-yuan, ZHENG Yuan-li, LI Jing. The effect of additional polyphosphazene nanotubes in polyurethane composites on microorganisms adhesion[J]. Shanghai Journal of Stomatology, 2014, 23(4): 419-422.

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