上海口腔医学

上海口腔医学 ›› 2025, Vol. 34 ›› Issue (2): 213-217.doi: 10.19439/j.sjos.2025.02.018

• 论著 • 上一篇    下一篇

光动力和激光在种植体周围炎辅助治疗中的生物力学效应和组织修复性比较

张骁, 杨慧   

  1. 内蒙古医科大学第四附属医院 口腔科,内蒙古 包头 014030
  • 收稿日期:2024-11-12 修回日期:2024-12-23 出版日期:2025-04-25 发布日期:2025-05-15
  • 通讯作者: 杨慧,E-mail：731296512@qq.com
  • 作者简介:张骁（1999-）,男,在读硕士研究生,E-mail：976060897@qq.com

Comparison of biomechanical effects and tissue reparability of photodynamic and laser in the adjuvant treatment of peri-implantitis

Zhang Xiao, Yang Hui   

  1. Department of Stomatology, the Fourth Affiliated Hospital of Inner Mongolia Medical University. Baotou 014030, Inner Mongolia Autonomous Region, China
  • Received:2024-11-12 Revised:2024-12-23 Online:2025-04-25 Published:2025-05-15

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摘要： 目的：比较光动力和激光在种植体周围炎辅助治疗中的生物力学效应和组织修复性。方法：选择2023年3月—2024年4月收治的112例种植体周围炎患者,随机分为对照组和试验组,每组56例。在常规对症治疗基础上,对照组进行光动力治疗,试验组进行激光治疗。比较2组治疗前、治疗后1、2、3个月的生物力学效应[种植体动度(implant mobility, IM)、周围骨组织密度变化(peri-implant bone density, PBD)和种植体近中和远中边缘骨吸收]、组织修复性[龈沟出血指数(sulcus1bleeding index, SBI)、菌斑指数(plaque index, PLI)和牙周探诊深度(probing depth, PD)]、炎性因子[白细胞介素6(interleukin-6, IL-6)、肿瘤坏死因子α(tumor necrosis factor, TNF-α)和基质金属蛋白酶8(matrix met alloproteinases-8, MMP8)]及牙龈卟啉单胞菌（Porphyromonas gingivalis,P.g）占总菌比例的变化。采用SPSS 26.0软件包对数据进行统计学分析。结果：治疗后1~3个月,2组患者IM、种植体近中、远中边缘骨吸收、SBI、PLI、PD、IL-6、TNF-α、MMP-8和P.g占总菌比例显著降低,PBD显著升高（P<0.05）。与对照组相比,试验组IM、PBD、种植体近中及远中边缘骨吸收、IL-6、TNF-α和MMP-8显著改善（P<0.05）;与试验组相比,对照组SBI、PLI、PD和P.g占总菌比例显著改善（P<0.05）。结论：光动力和激光均可用于种植体周围炎辅助治疗,光动力疗法在组织修复性及降低P.g占总菌比例方面具有优势,激光在生物力学效应及降低炎性因子方面具有优势。

关键词: 光动力疗法, 激光治疗, 种植体周围炎, 生物力学效应, 组织修复

Abstract: PURPOSE: To compare the biomechanical effects and tissue reparability of photodynamic and laser in the adjuvant treatment of peri-implantitis. METHODS: A total of 112 patients with peri-implantitis who were diagnosed and treated from March 2023 to April 2024 were randomly divided into the control group and the experimental group, with 56 cases in each group. On the basis of conventional symptomatic treatment, the control group received photodynamic therapy and the experimental group received laser therapy. The biomechanical effects [implant mobility(IM), peri-implant bone density(PBD), mesial and distal marginal bone resorption of the implant], tissue reparability[sulcus bleeding index (SBI), plaque index (PLI) and probing depth (PD)], inflammatory factors [interleukin-6 (IL-6), tumor necrosis factor (TNF-α), and matrix metalloproteinases-8(MMP-8)] and the proportion of Porphyromonas gingivalis(P.g) in the total bacterial count were compared before and 1, 2, and 3 months after treatment between the two groups. SPSS 26.0 software package was used for statistical analysis of the data. RESULTS: After 1-3 months of treatment, both groups showed significant decrease in IM, mesial and distal marginal bone resorption of the implant, SBI, PLI, PD, IL-6, TNF-α, MMP8, and the proportion of P.g to total bacteria (P<0.05), and significant increase in PBD (P<0.05). Compared with the control group, the experimental group showed significant improvements in IM, PBD, mesial and distal marginal bone resorption of the implant, IL-6, TNF-α and MMP8 (P<0.05). Compared with the experimental group, the control group showed significant improvements in SBI, PLI, PD and the proportion of P.g to total bacteria (P<0.05). CONCLUSIONS: Both photodynamic and laser therapy can be used in the adjuvant treatment of peri-implantitis. Photodynamic therapy has advantages in tissue repair and reducing the proportion of P.g to total bacteria, while laser therapy has advantages in biomechanical effects and reducing inflammatory factors.

Key words: Photodynamic therapy, Laser therapy, Peri-implantitis, Biomechanical effects, Tissue repair

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