890例颌骨成釉细胞瘤临床病理分析

上海口腔医学 ›› 2015, Vol. 24 ›› Issue (3): 338-340.

890例颌骨成釉细胞瘤临床病理分析

刘浏,张新宇,胡永杰,张陈平,张志愿

上海交通大学医学院附属第九人民医院·口腔医学院口腔颌面-头颈肿瘤科,上海市口腔医学重点实验室,上海 200011

收稿日期:2015-01-09 出版日期:2015-06-20 发布日期:2015-07-24
通讯作者: 胡永杰, E-mail:drhuyongjie@126.com
作者简介:刘浏（1977-）,男,博士,E-mail:cycstal2002@126.com
基金资助:
上海交通大学医学院附属第九人民医院口腔颌面-头颈肿瘤科“苗圃”科研基金

Clinical and pathological analysis of jaw ameloblastomas in 890 patients

LIU Liu,ZHANG Xin-yu,HU Yong-jie,ZHANG Chen-ping,ZHANG Zhi-yuan

Department of Oromaxillofacial Head and Neck Surgery, Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine;Shanghai Key Laboratory of Stomatology. Shanghai 200011, China

Received:2015-01-09 Online:2015-06-20 Published:2015-07-24
Supported by:
Scientific Research Fund of Oromaxillofacial Head and Neck Surgery of Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine

摘要/Abstract

摘要： 目的:了解颌骨成釉细胞瘤的临床病理现状, 为临床诊疗提供帮助。方法:回顾性分析2003年1月—2014年6月间于我科住院治疗的890例颌骨成釉细胞瘤的临床病理资料,对其性别、年龄、发病部位、病理表现、治疗方法进行分析。结果:890例成釉细胞瘤患者中,平均年龄40.15岁,男女比例1.62:1。下颌骨受累724例(81.35%),上颌骨受累166例(18.65%),左右颌骨发病率基本相同,颌骨任一部位均可发生。病理亚型中,实体型378例,单囊型427例,是成釉细胞瘤最为常见的病理亚型。治疗方面,414例患者接受刮治手术,212例接受开窗手术,264例接受截骨手术。结论:成釉细胞瘤好发于青年,多见于下颌骨;男性发病率较女性高,下颌磨牙及下颌支区为最易受累部位;实体型及单囊型为最常见的病理亚型,刮治术为最常见的治疗方式。

关键词: 成釉细胞瘤, 临床分析, 病理分析, 颌骨

Abstract: PURPOSE: To investigate the clinical and pathological features of jaw ameloblastomas in 890 patients, in order to provide reference for clinical diagnosis and treatment. METHODS: Eight hundred and ninty cases with jaw ameloblastomas treated in our department from January 2003 to June 2014 were retrospectively analyzed, including their gender, age, primary sites, pathological subtypes and therapies. RESULTS: The age of patients ranged from 6 to 101 years old, with a mean age of 40.15 years. The distribution between males and females were 61.91% (551/890) males to 38.08% (339/890) females (1.62:1). 724 (81.35%) were located in the mandible, 166 (18.65%) were located in the maxilla. The occurrence of jaw ameloblastomas in this series of 890 patients was same in both sides of the jaw. Jaw ameloblastomas occurred in any parts of the jaw. Solid (378/890) and unicystic ameloblastoma (427/890) were the most common pathological subtypes. 414 cases underwent curettage, 212 cases underwent decompression, and 264 cases underwent mandibulectomy or maxillectomy. CONCLUSIONS: Jaw ameloblastoma mainly happens in mandible and young people. Men are more vulnerable to suffer from than women. The most common sites are mandibular molar region and ramus. Curettage is the most commonly used treatment for ameloblastomas.

Key words: Ameloblastoma, Clinical analysis, Pathological analysis, Jaw

中图分类号:

R739.8

刘浏,张新宇,胡永杰,张陈平,张志愿. 890例颌骨成釉细胞瘤临床病理分析[J]. 上海口腔医学, 2015, 24(3): 338-340.

LIU Liu,ZHANG Xin-yu,HU Yong-jie,ZHANG Chen-ping,ZHANG Zhi-yuan. Clinical and pathological analysis of jaw ameloblastomas in 890 patients[J]. Shanghai Journal of Stomatology, 2015, 24(3): 338-340.

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