Abstract: PURPOSE: Caries prevention for preschool children (aged 3-6 years) was always the focus of oral public health work for children. The purpose of this study was to explore the caries prevention effect of multi-dimensional oral cleaning intervention model for regional preschool children in shanghai. METHODS: Twelve kindergartens were randomly selected and divided into control group and experimental group（each group with 300 children aged 3-4 years old） in October 2016. Children in the control group received routine oral health education, while children in the experimental group adopted multi-dimensional oral cleaning intervention model. After 2 years of follow-up, oral cleaning behavior and caries status of children were analyzed with SPSS 22.0 software package. RESULTS: The experimental group was significantly higher than the control group in brushing frequency, brushing time, correct brushing method, fluoride toothpaste and floss using (P<0.01), and caries rate and dmft index of the experimental group were significantly lower than the control group(P<0.01). CONCLUSIONS: For caries prevention in preschool children, multi-dimensional oral cleaning intervention mode plays a positive and effective role in changing children's and parents' oral health knowledge, trust and practice. It also guides and monitors parents to conduct effective oral cleaning behavior in preschool children and reduce the risk of caries.

Key words: Oral disease prevention, Preschool children, Oral cleaning behavior, Caries