iRoot BP Plus联合Nd∶YAG激光治疗龋源性露髓的疗效评价

doi:10.19439/j.sjos.2025.02.009

上海口腔医学 ›› 2025, Vol. 34 ›› Issue (2): 162-165.doi: 10.19439/j.sjos.2025.02.009

iRoot BP Plus联合Nd∶YAG激光治疗龋源性露髓的疗效评价

周玉英¹, 张旭¹, 袁娟²

1.湖南省职业病防治院口腔医学中心;
2.中毒医学科,湖南长沙 410007

收稿日期:2024-10-22 修回日期:2024-12-16 出版日期:2025-04-25 发布日期:2025-05-15
通讯作者: 袁娟,E-mail：shu404@126.com
作者简介:周玉英（1971-）,女,本科,副主任医师,E-mail：15173195675@163.com
基金资助:
湖南省卫生健康委科研计划项目（202212074762）

Evaluation of the efficacy of iRoot BP Plus combined with Nd∶YAG laser in the treatment of cariogenic pulp exposure

Zhou Yuying¹, Zhang Xu¹, Yuan Juan²

1. The Center for Oral Medicine,
2. Department of Poisoning Medicine, Hunan Provincial Occupational Disease Prevention and Control Hospital. Changsha 410007, Hunan Province, China

Received:2024-10-22 Revised:2024-12-16 Online:2025-04-25 Published:2025-05-15

摘要/Abstract

摘要： 目的：探讨iRoot BP Plus联合Nd∶YAG激光治疗龋源性露髓的盖髓效果及对牙髓活力、咬合功能恢复的影响。方法：选择2022年1月—2023年1月治疗的196例龋源性露髓患者,患牙268颗（均为恒牙）,采用电脑随机数法分为试验组98例（136颗）和对照组98例（132颗）。2组清理龋坏组织后均行Nd:YAG激光治疗,试验组采用iRoot BP Plus充填,对照组采用矿物三氧化聚合体（mineral trioxide polymer,MTA）充填,比较2组治疗效果、牙髓活力及咬合功能。采用SPSS 24.0软件包对数据进行统计学分析。结果：治疗后3、6、12个月,2组治疗成功率相比,差异无统计学意义（P>0.05）。治疗后12个月,试验组咬合力与咀嚼效率显著高于对照组（P<0.05）。治疗后3、6、12个月,2组牙髓活力及牙髓内血流量较术前显著下降（P<0.05）;试验组牙髓活力及牙髓内血流量显著高于对照组（P<0.05）。结论：iRoot BP Plus联合Nd∶YAG激光治疗龋源性露髓,有助于保留牙髓活力,改善咬合功能。

关键词: 龋源性露髓, iRoot BP Plus, Nd∶YAG激光, 牙髓活力

Abstract: PURPOSE: To evaluate the pulp capping effect of iRoot BP Plus combined with Nd: YAG laser irradiation in the treatment of caries induced exposed pulp and its impact on pulp vitality and occlusal function recovery. METHODS: From January 2022 to January 2023, a total of 196 patients with dental caries and exposed pulp, including 268 permanent teeth, were selected and randomly divided into the experimental group of 98 patients (136 teeth) and control group of 98 patients (132 teeth) using computer randomization. Both groups were treated with Nd:YAG laser after cleaning the caries. The experimental group was filled with iRoot BP Plus and the control group was filled with mineral trioxide polymer (MTA). The treatment efficacy, pulp vitality and occlusal function were compared between the two groups. SPSS 24.0 software package was used for statistical analysis of the data. RESULTS: There was no significant difference in the success rate of treatment between the two groups at 3, 6 and 12 months after surgery(P>0.05). At 12 months after treatment, the bite force and chewing efficiency of the experimental group were significantly higher than those of the control group(P<0.05). At 3, 6 and 12 months after treatment, the pulp vitality and pulp blood flow in both groups significantly decreased compared to preoperative levels (P<0.05); the pulp vitality and pulp blood flow of the experimental group were significantly higher than those of the control group(P<0.05). CONCLUSIONS: iRoot BP Plus combined with Nd∶YAG laser in the treatment of cariogenic exposed pulp is helpful to preserve pulp vitality and improve occlusal function.

Key words: Cariogenic exposed pulp, iRoot BP Plus, Nd: YAG laser, Dental pulp vitality

中图分类号:

R781.1

周玉英, 张旭, 袁娟. iRoot BP Plus联合Nd∶YAG激光治疗龋源性露髓的疗效评价[J]. 上海口腔医学, 2025, 34(2): 162-165.

Zhou Yuying, Zhang Xu, Yuan Juan. Evaluation of the efficacy of iRoot BP Plus combined with Nd∶YAG laser in the treatment of cariogenic pulp exposure[J]. Shanghai Journal of Stomatology, 2025, 34(2): 162-165.

参考文献

[1] Arandi NZ, Thabet M.Minimal intervention in dentistry: a literature review on biodentine as a bioactive pulp capping material[J]. Biomed Res Int, 2021, 2021:5569313.
[2] Edwards D, Bailey O, Stone SJ, et al.How is carious pulp exposure and symptomatic irreversible pulpitis managed in UK primary dental care?[J]. Int Endod J, 2021, 54(12):2256-2275.
[3] Zhou L, Shi W, Zhang X, et al.Injectable tannin-containing hydroxypropyl chitin hydrogel as novel bioactive pulp capping material accelerates repair of inflamed dental pulp[J]. Biomolecules, 2024, 14(9): 1129.
[4] Afkhami F, Rostami G, Xu C, et al.The application of lasers in vital pulp therapy: a review of histological effects[J]. Lasers Med Sci, 2023, 38(1):215.
[5] Cushley S, Duncan HF, Lappin MJ, et al.Efficacy of direct pulp capping for management of cariously exposed pulps in permanent teeth: a systematic review and meta-analysis[J]. Int Endod J, 2021, 54(4):556-571.
[6] Fasoulas A, Keratiotis G, Spineli L, et al.Comparative efficacy of materials used in patients undergoing pulpotomy or direct pulp capping in carious teeth: a systematic review and meta-analysis[J]. Clin Exp Dent Res, 2023, 9(6):1129-1148.
[7] 潘耀耀, 马晓楠, 陈呈. iRoot BP plus对成人龋源性露髓治疗疗效及对牙髓血流的影响[J]. 上海口腔医学, 2024, 33(2): 160-163.
[8] Duncan HF.Present status and future directions-Vital pulp treatment and pulp preservation strategies[J]. Int Endod J, 2022, 55(Suppl 3):497-511.
[9] Mente J, Hieber F, Sekundo C, et al.MTA matrix technique: restoration of teeth with deep subgingival defects extending down to the osseous crest[J]. J Adhes Dent, 2022, 24:269-278.
[10] Joshi SR, Palekar AU, Pendyala GS, et al.Clinical success of platelet-rich fibrin and mineral trioxide aggregate(MTA) or MTA-like agents in healing of periapical lesion in nonsurgically treated pulpless immature permanent teeth: a systematic review[J]. J Int Soc Prev Community Dent, 2020, 10(4):379-383.
[11] Kunert M, Lukomska-Szymanska M.Bio-inductive materials in direct and indirect pulp capping-a review article[J]. Materials (Basel), 2020,13(5):1204.
[12] Zhang L, Yin L, Wu J, et al.Clinical influencing factors of vital pulp therapy on pulpitis permanent teeth with 2 calcium silicate-based materials: a randomized clinical trial[J]. Medicine (Baltimore), 2024, 103(18): e38015.
[13] Zhang D, Zheng C, Zhu T, et al.Identification of key module and hub genes in pulpitis using weighted gene co-expression network analysis[J]. BMC Oral Health, 2023, 23(1): 2.
[14] 张艳梅, 操小马, 王艳平. Nd∶YAG激光照射联合iRoot BP Plus材料行直接盖髓术治疗龋源性牙髓炎对患者炎症水平及牙髓活力的影响[J]. 临床和实验医学杂志, 2023, 22(2): 202-206.
[15] Afkhami F, Rostami G, Xu C, et al.The application of lasers in vital pulp therapy: clinical and radiographic outcomes[J]. BMC Oral Health, 2024, 24(1):333.
[16] 王冕, 姚莉莉, 韩爽, 等. 双波长激光联合生物陶瓷材料iRoot SP辅助磨牙根管治疗效果分析[J]. 上海口腔医学, 2024, 33(4): 421-425.
[17] Yang N, Yang W, Shen R, et al.In vitro and in vivo evaluation of iRoot BP Plus as a coronal sealing material for regenerative endodontic procedures[J]. Clin Oral Investig, 2024, 28(1): 70-81.
[18] Han S, Zhang Q.Vital pulp therapy following pulpotomy in immature permanent teeth with carious exposure[J]. J Clin Pediatr Dent, 2023, 47(5): 65-72.
[19] Huang X, Ge X, Fu W, et al.Effects of novel nanoparticulate bioceramic endodontic material on human dental pulp stem cells in vitro[J]. Int Dent J, 2024, 74(3): 482-491.
[20] Ma X, Xu H, Chen X, et al.Modern methods and materials used to treat root perforation: effectiveness comparison[J]. J Mater Sci Mater Med, 2024, 35(1): 1-11.
[21] Nakashima M, Tanaka H.Pulp regenerative therapy using autologous dental pulp stem cells in a mature tooth with apical periodontitis: a case report[J]. J Endod, 2024, 50(2): 189-195.
[22] 李国正, 石梦, 王昊. 应用不同介质及不同测试位点进行牙髓电活力测试的评价[J]. 北京口腔医学, 2022, 30(4): 260-263.
[23] 苏征, 杨子, 安婷, 等. 激光活化技术对细菌生物膜的清除效果[J]. 口腔医学研究, 2023, 39(7): 607-612.
[24] 苏征, 杨子. Nd∶YAG激光根管清理对纤维桩粘接效果的影响[J]. 口腔颌面修复学杂志, 2023, 24(4): 271-275.
[25] Hu X, Li Y, Xu J, et al.Immature permanent incisors with complicated crown fractures treated with partial pulpotomy using white mineral trioxide aggregate and iRoot BP plus-a retrospective long-term study[J]. Dent Traumatol, 2023, 39(2): 165-172.
[26] Zeng Q, Zhou C, Li M, et al.Concentrated growth factor combined with iRoot BP Plus promotes inflamed pulp repair: an in vitro and in vivo study[J]. BMC Oral Health, 2023, 23(1): 225-238.

iRoot BP Plus联合Nd∶YAG激光治疗龋源性露髓的疗效评价

Evaluation of the efficacy of iRoot BP Plus combined with Nd∶YAG laser in the treatment of cariogenic pulp exposure

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 5

编辑推荐

Metrics

本文评价

[1]	孙艳妮, 赵蕾, 刘伟, 殷晓萍. iRoot BP plus 与MTA根尖屏障术治疗年轻恒牙慢性根尖周炎的疗效比较[J]. 上海口腔医学, 2024, 33(3): 260-264.
[2]	潘耀耀, 马晓楠, 陈呈. iRoot BP plus对成人龋源性露髓治疗疗效及对牙髓血流的影响[J]. 上海口腔医学, 2024, 33(2): 160-163.
[3]	何花, 乌丹旦, 钟萍萍. 延续性口腔健康教育对全脱位患牙固定治疗效果的影响[J]. 上海口腔医学, 2021, 30(3): 288-291.
[4]	王静, 方滕姣子, 刘鹤. iRoot BP Plus 对脱落乳牙牙髓干细胞和人牙髓干细胞生物学行为的影响[J]. 上海口腔医学, 2019, 28(3): 251-258.
[5]	史爽, 包志凡, 陈旭, 张丹丹. 新型牙髓治疗材料iRoot BP Plus对人牙龈成纤维细胞的细胞毒性[J]. 上海口腔医学, 2014, 23(6): 681-684.