多发性骨髓瘤伴口腔淀粉样变性1例报告及文献复习

上海口腔医学 ›› 2016, Vol. 25 ›› Issue (5): 638-640.

• 病例报告 • 上一篇

多发性骨髓瘤伴口腔淀粉样变性1例报告及文献复习

李暖, 尚伟, 杨学财, 宋凯

青岛大学附属医院口腔颌面外科,山东青岛 266000

收稿日期:2015-11-18 修回日期:2016-01-14 出版日期:2016-10-25 发布日期:2016-11-10
通讯作者: 尚伟,E-mail:liweishang@126.com
作者简介:李暖（1989-）,女,在读硕士研究生,E-mail:sdyzsy2008@126.com

Multiple myeloma with oral amyloidosis: report of a case and literature review

LI Nuan, SHANG Wei, YANG Xue-cai, SONG Kai

Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Qingdao University. Qingdao 266000, Shandong Province,China

Received:2015-11-18 Revised:2016-01-14 Online:2016-10-25 Published:2016-11-10

摘要/Abstract

摘要： 多发性骨髓瘤是浆细胞病中最常见的一种类型,但同时伴发口腔多部位淀粉样变性的病例罕见,其临床表现复杂多样,易误诊、漏诊,从而延误治疗,危及生命。本文报告多发性骨髓瘤合并舌、牙龈、颊、髁突等多处淀粉样变性1例,并进行相关文献复习。

关键词: 多发性骨髓瘤, 口腔, 淀粉样变性

Abstract: [SummaryMultiple myeloma is the most common type of multifocal plasma cell proliferation in the bone marrow, whereas cases with multiple amyloidosis of oral cavity are rarely documented. Clinically, the disease is easily miss- diagnosed and mistreated due to lack of specificity. This article reported a rare case with multiple myeloma and amyloidosis of tongue, gingiva, buccal mucosa, followed by a review of relevant literature.

Key words: Multiple myeloma, Oral cavity, Amyloidosis

中图分类号:

R739.8

李暖, 尚伟, 杨学财, 宋凯. 多发性骨髓瘤伴口腔淀粉样变性1例报告及文献复习[J]. 上海口腔医学, 2016, 25(5): 638-640.

LI Nuan, SHANG Wei, YANG Xue-cai, SONG Kai. Multiple myeloma with oral amyloidosis: report of a case and literature review[J]. Shanghai Journal of Stomatology, 2016, 25(5): 638-640.

参考文献

[1] Dimopoulos M, Kyle R, Fermand JP, et al. Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3 [J]. Blood, 2011, 117(18): 4701-4705.
[2] Van de Donk NW, Lokhorst HM, Anderson KC, et al. How I treat plasma cell leukemia [J]. Blood, 2012, 120(12): 2376-2389.
[3] Romano A, Marescalco MS, Liardo C, et al. Oral lesion as unusual first manifestation of multiple myeloma: case reports and review of the literature [J]. Case Rep Hematol, 2014, 2014: 529452.
[4] Nam KU, Ahn J, Hong J. Occurrence of multiple myeloma in the head and neck:a report of two cases [J]. J Korean Assoc Oral Maxillofac Surg, 2013, 39(3): 139-143.
[5] Merlini G, Palladini G. Amyloidosis: is a cure possible? [J]. Ann Oncol, 2008, 19(Suppl 4): 63-66.
[6] Gjeorgjievski M, Purohit T, Amin MB, et al. Upper gastrointestinal bleeding from gastric amyloidosis in a patient with smoldering multiple myeloma [J]. Case Rep Gastrointest Med, 2015, 2015: 320120.
[7] Agarwal A, Singla S, Bansal M, et al. Bilateral pleural effusions due to pulmonary amyloidosis as the presenting manifestation of multiple myeloma [J]. Mediterr J Hematol Infect Dis, 2012, 4(1): e2012010.
[8] Basha HI, Raj E, Bachuwa G. Cardiac amyloidosis masquerading as biventricular hypertrophy in a patient with multiple myeloma[J]. BMJ Case Rep, 2013, 2013.
[9] Andreadis D, Poulopoulos A, Papadopoulos P, et al. Localized tongue amyloidosis in a patient with neurofibromatosis type II [J]. Head Neck Pathol, 2011, 5(3): 302-305.
[10] Li Y, Liu N, Xu Y, et al. Widespread purple bulla-like masses of the oral mucosa [J]. Oral Surg Oral Med Oral Pathol Oral Radiol, 2012, 114 (5): 552-557.
[11] Babburi S, B R, Rv S, et al. Amyloidosis of the tongue-report of a rare case [J]. J Clin Diagn Res, 2013, 7(12): 3094-3095.
[12] Memari F, Jahandideh H, Moghtader K, et al. Narrowing of the upper airway due to amyloidosis: a case report [J]. J Clin Med Res, 2011, 3(4): 52-56.
[13] Oliveira EV, Pozetti AC, Pozetti EM, et al. Primary systemic amyloidosis associated with multiple myeloma [J]. An Bras Dermatol, 2012, 87(1): 119-122.

[1]	孙少宣. 中国口腔医学美学推动者: 深切怀念中国工程院邱蔚六院士[J]. 上海口腔医学, 2024, 33(4): 337-338.
[2]	赵娇, 隋佰延, 刘昕, 阮敏. 口腔鳞状细胞癌免疫相关预后风险模型的构建与验证[J]. 上海口腔医学, 2024, 33(4): 345-353.
[3]	谭军艳, 李莉, 杨玉娥, 王伟, 汪隼. 自闭症患儿口腔健康状况及家长认知程度调查分析[J]. 上海口腔医学, 2024, 33(4): 403-406.
[4]	翟利云, 姚宁, 孔佳新, 丁志民, 徐杨, 赵超男. 学龄前儿童龋病相关口腔健康行为潜在类别及异质关联分析[J]. 上海口腔医学, 2024, 33(4): 415-420.
[5]	贾爽, 王珏, 钟群, 陈骊, 卢汉. PDCA循环带教模式在口腔修复学住院医师规范化培训教学中的应用[J]. 上海口腔医学, 2024, 33(4): 438-442.
[6]	何文瑶, 郑沛. 实习期口腔医学生叙事医学实践的初步探索[J]. 上海口腔医学, 2024, 33(4): 443-448.
[7]	魏子程, 周晨, 季炼, 侯德强, 董煜. 海奥口腔生物膜单独或联合同种异骨体对颌骨囊肿术后骨缺损修复效果比较[J]. 上海口腔医学, 2024, 33(3): 285-289.
[8]	谢玉婷, 熊屏. 基于单原子铁纳米催化剂的纳米催化疗法对口腔鳞癌细胞Cal27的作用[J]. 上海口腔医学, 2024, 33(2): 117-122.
[9]	赵炅, 白果, 杨驰. 口腔黏膜成纤维细胞的单细胞转录组特征[J]. 上海口腔医学, 2024, 33(1): 1-5.
[10]	郝妍, 白相宇, 霍峰, 陈喜波. 下调SETDB1通过SOX7甲基化抑制口腔癌上皮-间充质转化、侵袭和转移的机制探讨[J]. 上海口腔医学, 2024, 33(1): 30-35.
[11]	康莹, 丁琴, 汪隼. 学龄前儿童家长对口腔不良习惯的认知调查[J]. 上海口腔医学, 2024, 33(1): 101-105.
[12]	赵燕, 张颖, 陈茜, 侯黎莉. 下颌骨缺损患者对咬合功能锻炼需求的质性研究[J]. 上海口腔医学, 2024, 33(1): 106-112.
[13]	叶赛, 张颖, 夏荣辉, 周永梅, 吴岚. 基于网络药理学及体外细胞学探讨野黄芩苷抑制口腔白斑癌变的作用机制[J]. 上海口腔医学, 2023, 32(6): 572-577.
[14]	刘文静, 李梦琦, 崔祥, 汪俊兰. circ_0000326靶向miR-567对口腔鳞状细胞癌HSC3细胞增殖、侵袭及迁移的调控效应[J]. 上海口腔医学, 2023, 32(6): 590-596.
[15]	陈兴金, 范然怡, 陶识丞, 薛睿, 文旭涛, 麦华明. 颈淋巴清扫术保留胸锁乳突肌与否对晚期口腔鳞癌预后的影响[J]. 上海口腔医学, 2023, 32(6): 609-614.

多发性骨髓瘤伴口腔淀粉样变性1例报告及文献复习

Multiple myeloma with oral amyloidosis: report of a case and literature review

RichHTML

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价