TMPT添加型牙本质封闭剂的改良研究

上海口腔医学 ›› 2014, Vol. 23 ›› Issue (5): 566-570.

TMPT添加型牙本质封闭剂的改良研究

周秦¹, 林彤², 谭文宏¹, 肖敏¹, 逯宜¹

1.西安交通大学口腔医院修复科,陕西西安 710004; 2.西安市第九医院口腔科,陕西西安 710054

收稿日期:2014-01-21 修回日期:2014-03-11 出版日期:2014-10-20 发布日期:2015-02-04
通讯作者: 逯宜,E-mail：Luyi1962@163.com
作者简介:周秦（1970-）,女,博士,主任医师,E-mail：zhouqin0529@126.com
基金资助:
陕西省科学技术研究发展计划项目（社发攻关2013K12-16-05）

A study on the development of TMPT-contained trial dentin sealant

ZHOU Qin¹, LIN Tong², TAN Wen-hong¹, XIAO Min¹, LU Yi¹

1.Stomatological Hospital of Xi’an Jiaotong University. Xi’an 710004; 2.Department of Stomatology, Ninth Hospital of Xi’an City. Xi’an 710054, Shaanxi Province, China

Received:2014-01-21 Revised:2014-03-11 Online:2014-10-20 Published:2015-02-04
Supported by:
; Supported by Science and Technology Development Fund of Shaanxi Province (2013K12-16-05)

摘要/Abstract

摘要： 目的探讨树脂固化体系配方对TMPT添加型试制牙本质封闭剂的黏结及聚合性能影响。方法以“劲润”牙本质保护膜（HyC）和前期实验试制的TMPT添加型牙本质封闭剂T33作为对照,调整其中樟脑醌（CQ）含量,配制6组CQ实验封闭剂,通过测试牙本质剪切黏结强度,找出黏结强度最大的 CQn组,作为下一步实验基材;调整HyC原装海绵中N-苯基甘氨酸（NPG）含量,配制5组NC实验海绵,测试其与CQn配合使用时的牙本质黏结强度和聚合转化率。采用SPSS13.0软件包对数据进行统计学分析。结果 CQ实验封闭剂组中,CQ3显示最大黏结强度,约12.99 MPa。以CQ3为基材,与各NPG实验海绵组配合使用时,NPG4.4和NPG7.3组显示最大黏结强度,约为14.68 MPa和14.69 MPa;同时也显示了最大聚合转化率,与对照组相比,差异显著（P<0.05）; 结论针对TMPT添加型试制牙本质封闭剂,当液体中CQ含量与专用海绵中NPG含量的摩尔比为1∶4.4或1∶7.3时,可在不降低材料聚合性能的同时,显著提高牙本质黏结强度,其材料学性能及远期效果有待于进一步证实。

关键词: 牙本质封闭剂, TMPT, 聚合转化率, CQ, 剪切黏结强度

Abstract: PURPOSE: To investigate the effect of resin curing system formulations of TMPT-contained trial dentin sealant on its bonding and polymerization properties. METHODS: Commercially available Hybrid Coat (HyC) and previously trial TMPT-contained dentin sealant T33 as control groups, adjusting camphorquinone (CQ) content to make CQ trial dentin sealants. Their dentin shear bond strength was tested to find the strongest group named CQn as the next test substrate. N-phenylglycine (NPG) content of original sponges was adjusted to make NC trial sponges. Bond strength and degree of conversion of CQn were tested using each NC trial sponges. The data was analyzed by SPSS13.0 software package. RESULTS：CQ3 showed the biggest bond strength in the group of CQ trial sealants of about 12.99 MPa. When CQ3 was used with every NPG trial sponges, NPG4.4 and NPG7.3 groups showed the statistically greatest bond strength of about 14.68 and 14.69 MPa (P<0.05). And NPG7.3 also showed the maximum degree of conversion of about 83.2%. CONCLUSIONS: The bonding strength and degree of conversion of trial TMPT-contained dentin sealant were the biggest when molar ratio of CQ and NPG was 1:4.4 or 7.3, but the material properties need to be tested in subsequent experiments.

Key words: Dentin sealant, TMPT, Degree of conversion, CQ, Shear bond strength

周秦, 林彤, 谭文宏, 肖敏, 逯宜. TMPT添加型牙本质封闭剂的改良研究[J]. 上海口腔医学, 2014, 23(5): 566-570.

ZHOU Qin, LIN Tong, TAN Wen-hong, XIAO Min, LU Yi. A study on the development of TMPT-contained trial dentin sealant[J]. Shanghai Journal of Stomatology, 2014, 23(5): 566-570.

参考文献

[1] Duarte S Jr, de Freitas CR, Saad JR, et al. The effect of immediate dentin sealing on the marginal adaptation and bond strengths of total-etch and self-etch adhesives [J]. J Prosthet Dent, 2009, 102(1): 1-9.
[2] Takahashi R, Nikaido T, Ariyoshi M, et al. Microtensile bond strengths of a dual-cure resin cement to dentin resin coated with an all-in-one adhesive system using two curing modes [J]. Dent Mater J, 2010, 29(3): 268-276.
[3] 黄莎, 杨胜德. 即刻牙本质封闭技术的研究进展 [J]. 口腔医学研究, 2012, 28(3): 282-283, 286.
[4] 陈锡平, 王庆, 毕玮, 等. 劲润（Hybrid Coat）治疗活髓牙全冠制备后牙本质过敏的临床研究 [J]. 中国临床医学, 2010, 17(3): 432-433.
[5] 二階堂徹, 來山修三, 高橋礼奈, 等. 間接法修復におけるレジンコーティングについて—「Super Dentin」の形成 [J]. 日本歯科評論, 2009, 69(1): 85-90.
[6] 湛渝, 马丁. 牙本质保护膜在烤瓷全冠牙体预备后的应用 [J]. 口腔颌面修复学杂志, 2011, 12(2): 97-99.
[7] Islam MR, Takada T, Weerasinghe DS, et al. Effect of resin coating on adhesion of composite crown restoration [J]. Dent Mater J, 2006, 25(2): 272-279.
[8] 周秦, 白乐康, 逯宜, 等. “劲润”牙本质保护膜的牙本质黏结性能探讨 [J]. 中国美容医学杂志, 2013, 22(1): 159-161.
[9] 周秦, 牛林, 刘越胜, 等. 添加TMPT的“劲润”牙本质保护膜粘结强度的研究 [J]. 西安交通大学学报(医学版), 2013, 34(4): 441-444.
[10] Guo X, Peng Z, Spencer P, et al. Effect of initiator on photopolymerization of acidic, aqueous dental model adhesives [J]. J Biomed Mater Res A, 2009, 90(4): 1120-1127.
[11] Suzuki S, Ori T, Saimi Y. Effects of filler composition on flexibility of microfilled resin composite[J]. J Biomed Mater Res B Appl Biomater, 2005, 74(1): 547-552.
[12] 姚科. 牙本质黏结剂的相分离现象[J]. 国际口腔医学杂志, 2010, 37(5): 580-582.
[13] Wakamatsu S, Ikemi T. Effect of polymerization accelerator on dentin bonding of one-step bonding agent [J]. Dent Mater J, 2007, 26(1): 7-13.
[14] Schneider LF, Cavalcante LM, Consani S, et al. Effect of co-initiator ratio on the polymer properties of experimental resin composites formulated with camphorquinone and phenyl-propanedione [J]. Dent Mater, 2009, 25(3): 369-375.
[15] 中林宣男, 石原一彦, 岩崎泰彦. バイオマテリアル [M]. 東京: コロナ社, 1999: 20-30.